Basic and Clinical Science

Event
June 5, 2019

Adherence 2019 will take place June 17-19, 2019, at the Loews Miami Beach Hotel in Miami, FL, USA.

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June 5, 2019

More adolescents and young adults living with HIV are surviving into adulthood. As a result they must transition from pediatric health services to HIV self-management and adult care.

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May 28, 2019
The 9th South African AIDS Conference took place from 11-14 June 2019 in Durban, South Africa, and the SHARE team was there to bring you updates, related content, and live coverage! The Conference focused on unprecedented scientific, social and digital innovations and technologies which could expand possibilities and opportunities towards controlling the HIV and AIDS epidemic. It also aimed to determine how contemporary explosive and disruptive technologies can contribute towards sustained HIV prevention efforts, HIV testing, ART uptake and adherence, trigger the development of new drugs, effectively utilise enormous volumes of data, and improve communication and service delivery, and eventually end the epidemic. Browse our dedicated SA AIDS 2019 page here.
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May 27, 2019

The USAID/TSP HIV Child and Adolescent ARV Procurement Forecasting Tool is intended to assist program managers, clinicians and support staff in quantifying and budgeting for a program’s child and adolescent ARV needs.

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May 12, 2019
In our 8th issue of our Research Digest, we have assembled 64 abstracts published from March through April 2019 that feature evidence from Botswana (2), Eswatini (2), Lesotho (2), Malawi (12), Mozambique (4), Namibia (1), South Africa (32), Tanzania (3), Zambia (11) and Zimbabwe (14).
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May 6, 2019
The level of evidence for HIV transmission risk through condomless sex in serodifferent gay couples with the HIV-positive partner taking virally suppressive antiretroviral therapy (ART) is limited compared with the evidence available for transmission risk in heterosexual couples. The aim of the second phase of the PARTNER study (PARTNER2) was to provide precise estimates of transmission risk in gay serodifferent partnerships.
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April 12, 2019
In the ART era, CAP in Malawi remains predominantly HIV-associated with a large proportion attributable to potentially vaccine-preventable pathogens. Strategies to increase early detection and treatment of tuberculosis and improve supportive care, in particular the correction of hypoxaemia, should be evaluated in clinical trials to address CAP-associated mortality.
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April 12, 2019
Subclinical tuberculosis is an asymptomatic disease phase with important relevance to persons living with HIV. We describe the prevalence, clinical characteristics, and risk of mortality for HIV-infected adults with subclinical tuberculosis.
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April 12, 2019
Community-based GeneXpert MTB/RIF testing may increase detection of prevalent TB in the community and improve rates of TB treatment completion.
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April 12, 2019
The tolerance of antiretroviral drugs in infants must be carefully evaluated. In previous studies of children with HIV type 1 (HIV-1) less weight gain was observed in children given lopinavir-ritonavir-based combinations than those given nevirapine. We aimed to compare the effects of lopinavir-ritonavir and lamivudine on growth in HIV-exposed uninfected infants included in the ANRS 12174 trial.