Final follow up of the HPTN 052 study of treatment as prevention shows no evidence of HIV transmission from people with fully suppressed viral load to their partners, four years after the first results from the study demonstrated that early HIV treatment reduced the risk of HIV transmission by 96
To estimate the potential reduction in HIV incidence, we constructed a risk equation based on a flow diagram of the HIV cascade, linking HIV diagnosis and treatment coverage with estimates of annual incidence and prevalence. This was applied to numerous settings.
Antiretroviral therapy (ART) is the most effective preventive strategy against tuberculosis in people with HIV, substantially reducing the risk irrespective of baseline CD4 cell count, tuberculin skin test status, and antimycobacterial drug resistance.
Tanzania’s strategic AIDS plan recognizes the impact of the country’s epidemic on people who inject drugs, as well as on other criminalized populations, including men who have sex with men, and people involved in sex work.