Basic and Clinical Science

Resource
November 13, 2019
Retention in care is associated with improved virological control and survival among HIV-infected children. However, retention of children in HIV care remains a challenge. This study demonstrates the value of routine laboratory data in monitoring diagnosis, retention and VL suppression in HIV-infected children. This approach is scalable, can be reported near real-time, is relatively inexpensive to implement, and provides a tool for improving paediatric HIV services until clinical databases can assume this role.
Resource
October 25, 2019
Routinely monitoring the HIV viral load (VL) of people living with HIV (PLHIV) on anti-retroviral therapy (ART) facilitates intensive adherence counselling and faster ART regimen switch when treatment failure is indicated. Yet standard VL-testing in centralized laboratories can be time-intensive and logistically difficult in low-resource settings. This paper evaluates the outcomes of the first four years of routine VL-monitoring using Point-of-Care technology, implemented by Medecins Sans Frontieres (MSF) in rural clinics in Malawi.
Resource
October 25, 2019

BACKGROUND: The NEVEREST-3 (South Africa) and MONOD-ANRS-12206 (Cote d'Ivoire, Burkina Faso) randomized trials found that switching to efavirenz (EFV

Resource
October 10, 2019
In this issue of the research Digest, we have assembled 86 abstracts published in July and August 2019 that feature evidence from Botswana (4), Burundi (1), Democratic Republic of Congo (1), Eswatini (3), Lesotho (4), Malawi (3), Mozambique (7), South Africa (51), Zambia (10) and Zimbabwe (9). Abstracts are grouped into linked categories to make browsing easier: Advocates (1); Health care providers (14); implementers and programmers (37); lay health workers (2); policymakers and government officials (1); and researchers (31).
Resource
October 10, 2019
For HIV-positive individuals on antiretroviral therapy (ART), the World Health Organization (WHO) recommends routine viral load (VL) monitoring. We report on the cascade of care in individuals with unsuppressed VL after introduction of routine VL monitoring in a district in Lesotho.
Resource
October 10, 2019

Increasing numbers of people living with HIV (PLHIV) in sub-Saharan Africa are experiencing failure of first-line antiretroviral therapy and transitioning onto second-line regimens. However, there is a dearth of research on their treatment experiences.

Resource
October 7, 2019

Early infant diagnosis (EID) of HIV provides an opportunity for early HIV detection and access to appropriate antiretroviral treatment (ART). Dried Blood Spot (DBS) samples are used for EID of exposed infants, born to HIV-positive mothers.

Event
October 2, 2019
The 23rd International AIDS Conference (AIDS 2020) is the premier global platform to advance the HIV response. As the world’s largest conference on HIV and AIDS, it sits uniquely at the intersection of science, advocacy and human rights, bringing together scientists, policy makers, healthcare professionals, people living with HIV, funders, media and community. AIDS 2020 will be hosted in San Francisco and Oakland, US, on 6-10 July 2020 under the theme "Resilience". Register now!
Blog
September 16, 2019

This has been a landmark year for HIV treatment; a seven-year study confirmed that taking ART can prevent transmission between gay couples and a second patient has been effectively cured of HIV after receiving a stem cell transplant as a cancer treatment.

Opportunity
September 5, 2019
Panagora South Africa has a Collaboration and Learning Hub that supports the USAID/South Africa Health Office with Expert Technical Services. This includes two activities, Technical Support Services (TSS) and Monitoring, Evaluation, Research and Learning (MERL), both of which help USAID meet its HIV and TB programs goals. Panagora is actively looking for creative, dynamic, results-focused and experienced professionals for a number of positions.