tuberculosis

A new point-of-care test to diagnose tuberculosis

In 2017, tuberculosis caused an estimated 1·6 million deaths, including 300 000 deaths among people with HIV, and surpassed HIV/AIDS to become the leading infectious cause of mortality worldwide. Approximately 36% of tuberculosis cases each year (around 3·5 million cases) are not diagnosed or reported, which might have contributed to the increase in tuberculosis prevalence.

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People's Country Operational Plan on HIV and TB (People's COP19)

With only a year until 2020 – and the deadline to reach the 90-90-90 targets – South Africa is dangerously off track. Currently 7.1 million people are living with HIV in the country. New HIV infections remain high, according to the Thembisa model1 at 275 000 in 2017, higher than the 231 000 estimated in the Human Sciences Research Council (HSRC) survey.

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The association between HIV infection and pulmonary function in a rural African population

OBJECTIVES: HIV infection has been associated with an impaired lung function in high-income countries, but the association between HIV infection and pulmonary function in Sub-Saharan Africa remains unclear. This study aims to investigate the relation between HIV infection and pulmonary function in a rural African population.

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Subclinical tuberculosis among adults with HIV: Clinical features and outcomes in a South African cohort

Subclinical tuberculosis is an asymptomatic disease phase with important relevance to persons living with HIV. We describe the prevalence, clinical characteristics, and risk of mortality for HIV-infected adults with subclinical tuberculosis.
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TB Data, Impact Assessment and Communications Hub (TB DIAH)

TB Data, Impact Assessment and Communications Hub (TB DIAH) is a new project that just launched a web-based, interactive data platform for global tuberculosis (TB) data users. TB DIAH is associated with the Global Accelerator to End TB, USAID’s new business model to focus on performance-based measures for combating TB.

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Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multicentre cohort study

Author
Kathrin Zürcher, Marie Ballif, Prof Lukas Fenner, Sonia Borrell, Peter M Keller, Joachim Gnokoro et al.
Drug resistance is a challenge for the global control of tuberculosis. We examined mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of results from drug susceptibility testing done locally and in a reference laboratory.
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WHO World TB Day 2019 campaign site

Each year, we commemorate World Tuberculosis (TB) Day on March 24 to raise public awareness about the devastating health, social and economic consequences of TB, and to step up efforts to end the global TB epidemic. The date marks the day in 1882 when Dr Robert Koch announced that he had discovered the bacterium that causes TB, which opened the way towards diagnosing and curing this disease.

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Transmission of drug-resistant tuberculosis in HIV-endemic settings

Author
Palwasha Y Khan, PhD; Tom A Yates, PhD; Muhammad Osman, MSc; Prof Robin M Warren, PhD; Yuri van der Heijden, MD; Nesri Padayatchi, PhD; et al.

The emergence and expansion of the multidrug-resistant tuberculosis epidemic is a threat to the global control of tuberculosis. Multidrug-resistant tuberculosis is the result of the selection of resistance-conferring mutations during inadequate antituberculosis treatment. However, HIV has a profound effect on the natural history of tuberculosis, manifesting in an increased rate of disease progression, leading to increased transmission and amplification of multidrug-resistant tuberculosis. Interventions specific to HIV-endemic areas are urgently needed to block tuberculosis transmission.

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It’s Time to Accelerate the TB Response

The first-ever UN high level meeting on tuberculosis (TB) on 26 September 2018 in New York was a crucial political moment for TB. It resulted in an endorsement of the first UN Political Declaration on TB [1], specifying prevention and treatment targets and commitments to mobilizing additional resources for the TB response, including research and development.

Author
Sharonann Lynch, HIV & TB Policy Advisor, Médecins Sans Frontières (MSF) Access Campaign
Source
Differentiated Service Delivery Blog
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