OBJECTIVES: HIV infection has been associated with an impaired lung function in high-income countries, but the association between HIV infection and pulmonary function in Sub-Saharan Africa remains unclear. This study aims to investigate the relation between HIV infection and pulmonary function in a rural African population.
HIV infection is not associated with the initiation of curative treatment in women with cervical cancer in Botswana
New Findings Presented at IAS 2017 Reveal More about the Inter-relationship Between the Microbiome and HIV
Over the past several years, research has uncovered just how important the microbiome is to human health. Catapulted by the Human Microbiome Project, researchers have begun to tap into a wealth of scientific knowledge showing us that the microbiome can affect and contribute to maintaining health, as well as impact the course of numerous diseases. Scientific publications on the microbiome have increased by 700% over the past six years. Several presentations at IAS 2017 focused on the microbiome.
Gaps in Adolescent Engagement in Antenatal Care and Prevention of Mother-to-Child HIV Transmission Services in Kenya
Rates of pregnancy and HIV infection are high among adolescents. However, their engagement in prevention of mother-to-child HIV transmission (PMTCT) services is poorly characterized. We compared engagement in the PMTCT cascade between adult and adolescent mothers in Kenya.
Preejaculatory fluid, a viscous, lubricating secretion expressed by penile urethral glands during sexual excitement, may play a role in the sexual transmission of HIV-1. The urethra has been shown to be an important site of HIV infection in men and male macaques, and preejaculatory fluid and urethral swabs from HIV-1-infected men often contain HIV. Recent studies have shown that HAART reduces but does not eliminate seminal HIV shedding in infected men, and that the penile urethra remains a site of persistent simian immunodeficiency virus infection in HAART-treated macaques.
The benefit of male circumcision is greatest among men who are most at risk of HIV infection. Encouraging this population of men to get circumcised maximizes the benefit that can be achieved through the scale-up of circumcision programs. This paper examines how the price of circumcision affects the risk profile of men who receive a voluntary medical circumcision.
2015 progress report on the global plan towards the elimination of new HIV infections among children and keeping their mothers alive
This is the fourth annual report of the Global Plan, and it summarizes the progress made through December 2014. The final accountability report of the Global Plan will be issued in 2016 when data for the end of 2015 will be available. The Global Plan was developed during 2010 by a Global Task Team (GTT) co-chaired by UNAIDS and the Government of the United States.
It is unlikely that one single approach will achieve a cure for HIV infection, delegates at a community cure workshop held the day before the Conference on Retroviruses and Opportunistic Infections (CROI 2015) in Seattle, USA, heard last week.
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers
Here we show that...B cell follicles constitute 'sanctuaries' for persistent SIV replication in the presence of potent anti-viral CD8+ T cell responses, potentially complicating efforts to cure HIV infection with therapeutic vaccination or T cell immunotherapy.