HIV-exposed infants

Impact of male partner involvement on mother-to-child transmission of HIV and HIV-free survival among HIV-exposed infants in rural South Africa: Results from a two phase randomised controlled trial

The Sub-Saharan Africa region still remains the epicentre of the global HIV/AIDS epidemic. With regards to new paediatric HIV infections, almost 90% of new HIV infections are among children (aged 0-14 years), largely through mother to child transmission. Male Partner Involvement in Prevention of Mother to Child Transmission programmes is now strongly advocated as being key in improving infant outcomes. This study describes the role of Male Partner Involvement on infant HIV infection and mortality survival in the first year among HIV-exposed infants born from HIV positive mothers.
Include in home page features rotation
Off

Prescription of Antibacterial Drugs for HIV-Exposed, Uninfected Infants, Malawi, 2004-2010

Antimicrobial drug resistance is a serious health hazard driven by overuse. Administration of antimicrobial drugs to HIV-exposed, uninfected infants, a population that is growing and at high risk for infection, is poorly studied. We therefore analyzed factors associated with antibacterial drug administration to HIV-exposed, uninfected infants during their first year of life.
Include in home page features rotation
Off

Early linear growth retardation: results of a prospective study of Zambian infants

Linear growth retardation is the most dominant nutritional problem globally. We aimed to describe linear growth trajectory among infants under 2 years of age using the WHO growth velocity standards.
Include in home page features rotation
Off

HIV-positivity among HIV-exposed infants in Lesotho in the era of Option B+

Is the resource available on the Internet?
Yes
Author
Tsigereda G. Belachew, Kieran Hartsough, Andrea Schaaf, Mahlompho Ntholeng, Tiffany G. Harris

Lesotho's HIV prevalence among pregnant women is 28%. In 2013, Lesotho's Prevention of Mother to Child Transmission (PMTCT) program adopted Option B+ and revitalized the village health worker (VHW) program to strengthen community level PMTCT. The national goal was to test 95% of HIV-exposed infants (HEI) at 2 and 18 months and reduce transmission rates to

We reviewed routinely collected PMTCT data of infants aged

Include in home page features rotation
Off

Prevention of mother-to-child transmission of HIV Option B+ cascade in rural Tanzania: The One Stop Clinic model

Is the resource available on the Internet?
Yes
Author
Anna Gamell, Lameck Bonaventure Luwanda, Aneth Vedastus Kalinjuma, Leila Samson, Alex John Ntamatungiro, Maja Weisser, Winfrid Gingo, Marcel Tanner, Christoph Hatz, Emilio Letang, Manuel Battegay

Background

Strategies to improve the uptake of Prevention of Mother-To-Child Transmission of HIV (PMTCT) are needed. We integrated HIV and maternal, newborn and child health services in a One Stop Clinic to improve the PMTCT cascade in a rural Tanzanian setting.

Methods

Include in home page features rotation
Off

Pre-exposure prophylaxis for infants exposed to HIV through breast feeding

Is the resource available on the Internet?
Yes
Author
Van de Perre Philippe, Kankasa Chipepo, Nagot Nicolas, Meda Nicolas, Tumwine James K, Coutsoudis Anna et al.

Uninfected pregnant or breastfeeding women in high incidence areas have been suggested as a potential target population for PrEP, but infants exposed to HIV through breastfeeding have not been mentioned. Numerous public declarations and petitions have produced a strong advocacy for extension of the PrEP principle to all high risk populations exposed to HIV, considering access to PrEP as part of human rights.

Include in home page features rotation
Off

CROI: Tenofovir/emtricitabine/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study finds

Is the resource available on the Internet?
Yes
Author
Carole Leach-Lemens

Infants exposed to an antiretroviral regimen of tenofovir, emtricitabine and efavirenz (Atripla) from conception experienced fewer adverse birth outcomes compared to other three-drug regimens, according to a study of births in Botswana between 2014 and 2016, presented on Tuesday at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle.

Include in home page features rotation
Off

Early-Infant Diagnosis: Bringing Infants into the HIV Equation

One of the last frontiers in the “no new HIV infections” goal is early infant diagnosis (EID): diagnosing and treating HIV-exposed and -positive infants. EID is urgent in the context of the epidemic: Up to 30 percent of HIV-positive babies will die within 12 months if not treated (EGPAF 2016). Aida Yemaneberhan, Technical Advisor for Prevention of Mother-to-Child Transmission (PMTCT) at AIDSFree, and Sabrina Eagan, Technical Advisor for Adult and Pediatric Treatment at AIDSFree, described the challenges of EID and what AIDSFree is doing to support this critical service.

Author
Sabrina Eagan, Technical Advisor for Adult and Pediatric Treatment, JSI, AIDSFree Project and Aida Yemaneberhan, Technical Advisor for PMTCT, EGPAF, AIDSFree Project
Source
The Pump

Time to implement 9-month infant HIV testing in South Africa

Is the resource available on the Internet?
Yes
Author
Fairlie L, Madevu-Matson CA, Black V, Sherman GG

BACKGROUND:

South Africa (SA) is likely to meet the National Strategic Plan target of

OBJECTIVE: To evaluate the impact of substituting this recommendation for the post-weaning HIV testing recommended by SA guidelines. 

Include in home page features rotation
Off

Point-of-care HIV early infant diagnosis: is test sensitivity everything?

Is the resource available on the Internet?
Yes
Author
Lorna Dunning, Nei-yuan Hsiao, Landon Myer

Despite improvements in PMTCT services in low- and middle-income countries, there are still almost 200,000 new paediatric HIV infections annually in sub-Saharan Africa. This has led to early infant HIV diagnosis (EID) programmes becoming a public health priority, but until recently, EID has required specialist laboratory equipment and trained personnel which is only feasible in urban, centralized facilities.

Include in home page features rotation
Off
Subscribe to HIV-exposed infants