To err is human, to correct is public health: a systematic review examining poor quality testing and misdiagnosis of HIV status
In accordance with global testing and treatment targets, many countries are seeking ways to reach the “90-90-90” goals, starting with diagnosing 90% of all people with HIV. Quality HIV testing services are needed to enable people with HIV to be diagnosed and linked to treatment as early as possible. It is essential that opportunities to reach people with undiagnosed HIV are not missed, diagnoses are correct and HIV-negative individuals are not inadvertently initiated on life-long treatment.
The Journal of the International AIDS Society just launched a supplement entitled ‘Programmatic and public health implications of misdiagnosis of HIV’. This supplement was guest edited by Cheryl C. Johnson (World Health Organization), Shona Dalal (World Health Organization) and Miriam Taegtmeyer (Liverpool School of Tropical Medicine).
Towards more accurate HIV testing in sub-Saharan Africa: a multi-site evaluation of HIV RDTs and risk factors for false positives
Although individual HIV rapid diagnostic tests (RDTs) show good performance in evaluations conducted by WHO, reports from several African countries highlight potentially significant performance issues. Despite widespread use of RDTs for HIV diagnosis in resource-constrained settings, there has been no systematic, head-to-head evaluation of their accuracy with specimens from diverse settings across sub-Saharan Africa.
Objective: To estimate time from HIV infection to linkage-to-care and its determinants. Linkage-to-care is usually assessed using the date of HIV diagnosis as the starting point for exposure time. However, timing of diagnosis is likely endogenous to linkage, leading to bias in linkage estimation.
Many countries are working to reduce or eliminate mother-to-child transmission (MTCT) of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low.
Guidelines on HIV self-testing and partner notification Supplement to consolidated guidelines on HIV testing services
Since the release of the consolidated guidelines in 2015, new evidence has emerged. Consequently, in an effort to further support countries, programme managers, health workers and other stakeholders seeking to achieve national and international HIV goals, this 2016 update issues new recommendations and additional guidance on HIV self-testing (HIVST) and assisted HIV partner notification services.
These new guidelines aim to: