HIV burden

The global response and unmet actions for HIV and sex workers

Author
Kate Shannon, Anna-Louise Crago, Stefan D Baral, Linda-Gail Bekker, Deanna Kerrigan, Michele R Decker, Tonia Poteat, Andrea L Wirtz, Brian Weir, Marie-Claude Boily, Jenny Butler, Steffanie A Strathdee, Chris Beyrer

Female, male, and transgender sex workers continue to have disproportionately high burdens of HIV infection in low-income, middle-income, and high-income countries in 2018. 4 years since our Lancet Series on HIV and sex work, our updated analysis of the global HIV burden among female sex workers shows that HIV prevalence is unacceptably high at 10·4% (95% CI 9·5–11·5) and is largely unchanged. Comprehensive epidemiological data on HIV and antiretroviral therapy (ART) coverage are scarce, particularly among transgender women.

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Guidelines on best practices for adolescent- and youth-friendly HIV services: An examination of 13 projects in PEPFAR-supported countries

Is the resource available on the Internet?
Yes
Author
Gage A, Do M, and Grant D

Adolescents (ages 10–19) and youth (ages 15–24) bear a disproportionate share of the HIV burden, especially in sub-Saharan Africa. However, little is known about what projects are doing to make their interventions adolescent- and youth-friendly and what interventions are effective for changing HIV-related outcomes for these age groups. Program managers and policymakers have little rigorous evidence on how best to invest resources to achieve 90-90-90 targets among adolescents and young people. Recognizing this evidence gap, MEASURE Evaluation—funded by the U.S.

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Best practices for adolescent- and youth-friendly HIV service: A compendium of selected projects in PEPFAR-supported countries

Is the resource available on the Internet?
Yes
Author
Gage A, Do M, and Grant D (eds.)

Adolescents (ages 10-19) and youth (ages 15-24) bear a disproportionate share of the HIV burden, especially in sub-Saharan Africa. However, little is known about what projects are doing to make their interventions adolescent- and youth-friendly and which interventions are effective for changing HIV-related outcomes in this age group. Program managers and policymakers have little evidence derived from rigorous studies on how best to invest resources to achieve 90-90-90 targets among adolescents/young people.

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The effects of caregiver and household HIV on child development: a community-based longitudinal study of young children

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Yes
Author
Sherr L, Skeen S, Hensels IS, Tomlinson M, Macedo A

Many studies that document child outcomes in the context of parental HIV - which has been established as a risk factor for child development - focus on older children/adolescents. Studies also concentrate on the status of the primary caregiver, not other household members who might be infected. This study examined the effects of caregiver and household HIV on child development (4-13 years) in South Africa and Malawi (2011-2014).

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Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting

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Yes
Author
Nivashnee Naicker, Ayesha B. M. Kharsany, Lise Werner, Francois van Loggerenberg, Koleka Mlisana, Nigel Garrett, Salim S. Abdool Karim

In South Africa young women bear a disproportionate burden of HIV infection however, risk factors for HIV acquisition are not fully understood in this setting. In a cohort of 245 women, we used proportional hazard regression analysis to examine the association of demographic, clinical and behavioural characteristics with HIV acquisition. The overall HIV incidence rate (IR) was 7.20 per 100 women years (wy), 95 % confidence interval (CI) 4.50–9.80.

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PANGEA-HIV: phylogenetics for generalised epidemics in Africa

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Yes
Author
Deenan Pillay, Joshua Herbeck, Myron S Cohen, Tulio de Oliveira, Christophe Fraser, Oliver Ratmann, Andrew Leigh Brown, Paul Kellam

Notable increases in coverage of antiretroviral treatment (ART) have been made in Africa in the past decade.

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