extensively drug-resistant TB (XDR-TB)

Estimating the future burden of multidrug-resistant and extensively drug-resistant tuberculosis in India, the Philippines, Russia, and South Africa: a mathematical modelling study

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Yes
Author
Sharma, Aditya et al.

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are emerging worldwide. The Green Light Committee initiative supported programmatic management of drug-resistant tuberculosis in 90 countries. We used estimates from the Preserving Effective TB Treatment Study to predict MDR and XDR tuberculosis trends in four countries with a high burden of MDR tuberculosis: India, the Philippines, Russia, and South Africa.

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Transmission of Extensively Drug-Resistant Tuberculosis in South Africa

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Yes
Author
N. Sarita Shah et al.

South Africa has one of the highest burdens of tuberculosis and drug-resistant tuberculosis in the world. In the past decade, the number of cases of XDR tuberculosis has increased by a factor of 10, to more than 1500 cases in 2012. Compounding the tuberculosis epidemic is the concurrent epidemic of HIV infection; rates of coinfection exceed 70%, and rates of long-term survival among patients with XDR tuberculosis and HIV infection are less than 20%. In this study, we sought to quantify the role of transmission and to elucidate how and where transmission is occurring.

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U.S. Government Roles in Control of Global Tuberculosis: Opportunities for Strengthening Program Effectiveness

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Yes
Author
Phillip Nieburg, Audrey Jackson

Over the first 15 years of this century, as efforts against the “big three” global infectious diseases — HIV, malaria and tuberculosis — accelerated, the numbers of new HIV infections dropped by 32 percent, and the number of deaths caused by the virus declined by 31 percent. Malaria infections dropped by 18 percent, and deaths from that disease went down by 48 percent.

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WHO Strategies for the programmatic management of drug-resistant tuberculosis

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Yes
Author
Matteelli, Centis, D'Ambrosio, et.al.

Adequate management of drug-resistant tuberculosis (TB), including multidrug- (MDR-) and extensively drug-resistant (XDR-)TB are within the priorities of the newly launched World Health Organization's End TB and Elimination Strategies.

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WHO recommendations on shorter treatment of multidrug-resistant tuberculosis

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Yes
Author
Giovanni Sotgiu, Simon Tiberi, Lia D'Ambrosio, Rosella Centis, Alimuddin Zumla, Giovanni Battista Migliori

Tuberculosis is now the world's commonest cause of death from infectious disease. The ominous spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis, and the scarce treatment options available, are priority global health issues. With a global estimate in 2014 of 450 000 cases of MDR and XDR tuberculosis causing 150 000 deaths, and the continuing spread, the WHO End TB Strategy highlights the threat that MDR and XDR tuberculosis pose to global public health security.

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The shorter MDR-TB regimen

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Yes
Author
World Health Organization (WHO)

Multidrug-resistant tuberculosis (MDR-TB) is a public health crisis and a global health security risk carrying grave consequences for those affected. An estimated 480 000 people developed MDR-TB in 2014 and 190 000 people died as a result of it. MDR-TB cannot be treated with the standard 6-month course of first-line medication which is effective in most TB patients. Patients with rifampicin-resistant or MDR-TB are treated with a different combination of second-line drugs, usually for 18 months or more.

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World TB Day 2016

Venue
Global

World TB Day is less than a month away! Taking place on March 24, this year’s theme is "Unite to End TB" – a call to action for everyone around the globe to come together to mobilize in the fight against TB, a preventable disease that still causes almost 1.5 million deaths a year, mostly in developing countries.

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47th Union World Conference on Lung Health

Venue
Liverpool, UK

The 47th Union World Conference on Lung Health is taking place in Liverpool, UK, from 26 to 29 October 2016.

TB is a curable and treatable disease, yet it was accountable for the deaths of 1.5 million people in 2014. Its effects are felt in all parts of the world – including the UK – and it poses real challenges for public health efforts globally.

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