drug-susceptible tuberculosis

The costs and outcomes of paediatric tuberculosis treatment at primary healthcare clinics in Johannesburg, South Africa

Author
Budgell EP, Evans D, Leuner R, Long L, Rosen S

Background: Little up-to-date information is available about the costs of providing drug-susceptible tuberculosis (DS-TB) treatment to paediatric patients in South Africa (SA), nor have actual costs incurred at clinics been compared with costs expected from guidelines.

Objective: To estimate actual and guideline treatment costs by means of a retrospective cohort analysis.

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Rapid impact of effective treatment on transmission of multidrug-resistant tuberculosis

Is the resource available on the Internet?
Yes
Author
Dharmadhikari, A. S; Mphahlele, M; Venter, K; Stoltz, A; Mathebula, R; Masotla, T; van der Walt, M; Pagano, M; Jensen, P; Nardell, E

BACKGROUND: Effective treatment for drug-susceptible tuberculosis (TB) rapidly renders patients non-infectious, long before conversion of sputum acid-fast smear or culture to negative. Multidrug-resistant TB (MDR-TB) patients on treatment are currently assumed to remain infectious for months. While the resources required for prolonged hospitalization are a barrier to the scale-up of MDR-TB treatment, the safety of community treatment is clear.

OBJECTIVES: To estimate the impact of treatment on infectiousness among MDR-TB patients.

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