co-infection

Time delay and associated mortality from negative smear to positive Xpert MTB/RIF test among TB/HIV patients: a retrospective study

he GeneXpert MTB/RIF Assay (Xpert(R)) is known to be a feasible, effective and a hopeful tool for rapid tuberculosis (TB) diagnosis and treatment. However, little is known about the time delay caused by initial negative sputum smear microscopy (NSSM), but consecutive positive Xpert TB test (PXTBt) and its association with TB mortality in resource-constrained settings. We aimed to estimate the median time delay between initial NSSM but consecutive PXTBt and TB treatment initiation and its association with TB mortality among TB/HIV co-infected patients in Beira, Mozambique.
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Subclinical tuberculosis among adults with HIV: Clinical features and outcomes in a South African cohort

Subclinical tuberculosis is an asymptomatic disease phase with important relevance to persons living with HIV. We describe the prevalence, clinical characteristics, and risk of mortality for HIV-infected adults with subclinical tuberculosis.
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Constructing care cascades for active tuberculosis: A strategy for program monitoring and identifying gaps in quality of care

Author
Ramnath Subbaraman, Ruvandhi R. Nathavitharana, Kenneth H. Mayer, Srinath Satyanarayana, Vineet K. Chadha, Nimalan Arinaminpathy, Madhukar Pai

The cascade of care is a model for evaluating patient retention across sequential stages of care required to achieve a successful treatment outcome. This approach was first used to evaluate HIV care and has since been applied to other diseases. The tuberculosis (TB) community has only recently started using care cascade analyses to quantify gaps in quality of care. In this article, we describe methods for estimating gaps (patient losses) and steps (patients retained) in the care cascade for active TB disease.

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Knowledge, risk perception and access to healthcare services for HIV and tuberculosis among university students in Johannesburg, South Africa

Author
D Evans, N Musakwa, C Nattey, J Bor, E Lonnermark, C Larshans, S Andreasson, P Nyasulu, L Long
An increasingly diverse body of students is entering university in South Africa. HIV and tuberculosis (TB) are pressing health issues for this vulnerable population and the university campus offers an opportunity to intervene with health promotion activities. This study describes knowledge and risk perception of TB and HIV among high school leavers entering tertiary education.
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4th Southern African HIV Clinicians Society Conference

The Southern African HIV Clinicians Society’s biannual conference, held in Johannesburg, South Africa, from 24-27 October 2018, focused on clinical content for HIV and TB health care workers in the region and featured a wide range of topics, from new antiretroviral drugs, AIDS-related complications, and opportunistic infections, to promoting adherence and ethical issues.

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Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review

Is the resource available on the Internet?
Yes
Author
Degenhardt L, Peacock A, Colledge S, Leung J, Grebely J, Vickerman P, Stone J, Cunningham EB, Trickey A, Dumchev K, Lynskey M, Griffiths P, Mattick RP, Hickman M, Larney S

Sharing of equipment used for injecting drug use (IDU) is a substantial cause of disease burden and a contributor to blood-borne virus transmission. We did a global multistage systematic review to identify the prevalence of IDU among people aged 15-64 years; sociodemographic characteristics of and risk factors for people who inject drugs (PWID); and the prevalence of HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV) among PWID.

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Call for Abstracts: 4th Southern African HIV Clinicians Society Conference

Closing date

The Southern African HIV Clinicians Society’s biannual conference focuses on clinical content for HIV and TB health care workers. The 2018 conference programme has been carefully designed to benefit all health care practitioners, with topics ranging from new antiretroviral drugs, AIDS-related complications, opportunistic infections, promoting adherence and ethical issues.

A score to predict and stratify risk of tuberculosis in adult contacts of tuberculosis index cases: a prospective derivation and external validation cohort study

Is the resource available on the Internet?
Yes
Author
Matthew J Saunders, Tom Wingfield, Marco A Tovar, Matthew R Baldwin, Sumona Datta, Karine Zevallos, Rosario Montoya, Teresa R Valencia, Jon S Friedland, Larry H Moulton, Robert H Gilman, Carlton A Evans

Contacts of tuberculosis index cases are at increased risk of developing tuberculosis. Screening, preventive therapy, and surveillance for tuberculosis are underused interventions in contacts, particularly adults. We developed a score to predict risk of tuberculosis in adult contacts of tuberculosis index cases.

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