Uptake of antiretroviral therapy and male circumcision after community-based HIV testing and strategies for linkage to care versus standard clinic referral: a multisite, open-label, randomised controlled trial in South Africa and Uganda

Dr Ruanne V Barnabas, Heidi van Rooyen, Elioda Tumwesigye, Justin Brantley, Prof Jared M Baeten, Alastair van Heerden, Bosco Turyamureeba, Philip Joseph, Meighan Krows, Katherine K Thomas, Torin T Schaafsma, Prof James P Hughes, Prof Connie Celum

Male circumcision decreases HIV acquisition by 60%, and antiretroviral therapy (ART) almost eliminates HIV transmission from HIV-positive people who are virally suppressed; however, coverage of these interventions has lagged behind targets. We aimed to assess whether community-based HIV testing with counsellor support and point-of-care CD4 cell count testing would increase uptake of ART and male circumcision.

March 24, 2016
Year of publication
2016
Countries
Tags
voluntary medical male circumcision (VMMC), HIV prevention, treatment, virally suppressed, pre-exposure prophylaxis (PrEP), treatment coverage, community-based HIV testing, community-based interventions, counsellor support, point-of-care CD4 testing, uptake of services, South Africa, Uganda

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This document includes:
 
  • A Strategic Development Summary (SDS) narrative communicating the epidemiologic and country/regional context; methods used for programmatic design; findings of integrated data analysis; and strategic direction for the investments and programs…

Objectives

To examine the association between testing in the 2010 HIV Testing and Counselling (HCT) campaign with HIV risk behaviours and enrolment on ART.

Study design

BACKGROUND:

Attrition along the HIV care continuum slows gains in mitigating the South African HIV epidemic. Understanding population-level gaps in HIV identification, linkage, retention in care and viral suppression is critical to target programming.

BACKGROUND:

The goal of virtual elimination of horizontal and mother-to-child HIV transmission in South Africa (SA) has been proposed, but there have been few systematic investigations of which interventions are likely to be most critical to reducing HIV incidence.