Retention in care among HIV-infected pregnant and breastfeeding women on lifelong antiretroviral therapy in Uganda: A retrospective cohort study

Simon Muhumuza, Evelyn Akello, Charity Kyomugisha-Nuwagaba, Rose Baryamutuma, Isaac Sebuliba, Ibrahim M. Lutalo, Edgar Kansiime, Linda N. Kisaakye, Agnes N. Kiragga, Rachel King, William Bazeyo, Christina Lindan

In 2013, Uganda updated its prevention of maternal-to-child transmission of HIV program to Option B+, which requires that all HIV-infected pregnant and breastfeeding women be started on lifelong antiretroviral therapy (ART) regardless of CD4 count. We describe retention in care and factors associated with loss to follow-up (LTFU) among women initiated on Option B+ as part of an evaluation of the effectiveness of the national program. The study found that retention of women who were initiated on Option B+ during the early phases of roll-out was only moderate, and could undermine the effectiveness of the program. Identifying reasons why women drop out and designing targeted interventions for improved retention should be a priority.

January 30, 2018
Year of publication
Resource types
Journal and research articles
PMTCT, prevention of mother-to-child transmission (PMTCT), option B+, lifelong antiretroviral therapy, antiretroviral therapy (ART), HIV-positive pregnant women, HIV-positive breastfeeding women, loss to follow-up, retention in care