Package of prophylaxis against infections reduces the risk of death for people starting HIV treatment very late
A package of enhanced prophylaxis against infections significantly reduced the risk of death in adults and children with advanced HIV disease after starting antiretroviral treatment in a randomised study, Professor James Hakim of the University of Zimbabwe told the 21st International AIDS Conference (AIDS 2016) in Durban, South Africa, last month.
Professor Hakim was presenting the results of the REALITY study, a large clinical trial designed to evaluate strategies for reducing the risk of death in people who start antiretroviral treatment with very low CD4 cell counts (below 100 cells/mm3). Late presentation with HIV disease, often with symptomatic disease, remains common in sub-Saharan Africa. The risk of death in the first six months after starting treatment remains high for adults and children.