For people who may have been exposed to HIV, knowledge is critical to making informed decisions about their future. An HIV test is a serious event with potentially serious outcomes. But no matter the result, the test provides vital information. A negative result is an opportunity to take deliberate steps to prevent future acquisition through prevention methods tailored to that individual’s risks. A positive test result—and a confirmatory diagnosis—is never welcome news, but for people living with HIV, it is a necessary first step towards a long and healthy life.