The burden of HIV: insights from the GBD 2010.

Ortblad KF, Lozano R, Murray CJ.

OBJECTIVES: To evaluate the global and country-level burden of HIV/AIDS relative to 291 other causes of disease burden from 1980-2010 using the Global Burden of Disease Study 2010 (GBD 2010) as the vehicle for exploration.

METHODS:: HIV/AIDS burden estimates were derived elsewhere as part of GBD 2010, a comprehensive assessment of the magnitude of 291 diseases and injuries from 1990 to 2010 for 187 countries. In GBD 2010, disability-adjusted life years (DALYs) are used as the measurement of disease burden. DALY estimates for HIV/AIDS come from UNAIDS' 2012 prevalence and mortality estimates, GBD 2010 disability weights, and mortality estimates derived from quality vital registration data.

RESULTS:: Despite recent declines in global HIV/AIDS mortality, HIV/AIDS was still the fifth leading cause of global DALYs in 2010.The distribution of HIV/AIDS burden is not equal across demographics and regions. In 2010, HIV/AIDS ranked as the leading DALY cause for ages 30 to 44 in both sexes and for 21 countries that fall into four distinctive blocks: Eastern and Southern Africa, Central Africa, the Caribbean, and Thailand. While a majority of the DALYs caused by HIV/AIDS are in high-burden countries, 20% of the global HIV/AIDS burden in 2010 was in countries where HIV/AIDS did not make the top 10 leading causes of burden.

CONCLUSIONS:: In the midst of a global economic recession, tracking the magnitude of the HIV/AIDS epidemic and its importance relative to other diseases and injuries is critical to effectively allocating limited resources and maintaining funding for effective HIV/AIDS interventions and treatments

September 12, 2013
Tags
HIV, AIDS, disease burden, Global Burden of Disease (GBD), disability-adjusted life years (DALYs), resource-limited settings, HIV Funding, treatment, HIV intervention

Similar Resources

This report presents progress made after two years of implementation of the ESA Commitment (2013-2015). Significant progress has already been made thanks to concerted action by governments, civil society, and development partners at national and regional level.

The U.S. Government is committed and working toward the goal of Ending Preventable Child and Maternal Deaths (EPCMD) in a generation. In June of 2014, the U.S.

Donor funding for HIV programs has flattened out in recent years, which limits the ability of HIV programs worldwide to achieve universal access and sustain current progress. This study examines alternative mechanisms for resource mobilization.

The Xpert MTB/RIF assay is an accurate test for the diagnosis of tuberculosis when an adequate sputum sample can be obtained; even in smear-negative tuberculosis the sensitivity is about 67%. Although the assay turnaround time is under 2 h, depending on the health-care setting, time to…

The United States is the world’s leading donor in global health.

By telling the stories of four inspiring individuals, EXPOSED brings viewers to the forefront of the race against tuberculosis. Watch the four-part series of short films on the global TB epidemic and the race to develop new tools to prevent it.

The main focus of this report is to review the risk factors for HIV among sex workers in sub-Saharan Africa, and the interventions that have been successfully implemented in this region.

Depuis le taux de fécondité des adolescentes jusqu’aux sommes dépensées pour la santé par les gouvernements, les Statistiques sanitaires mondiales ont réponse à toutes vos questions sur la santé des populations dans le monde.

World Health Statistics 2012 contains WHO’s annual compilation of health-related data for its 194 Member States, and includes a summary of the progress made towards achieving the health-related Millennium Development Goals (MDGs) and associated targets.