Resource Library

Introduction: ARV-based pre-exposure prophylaxis (PrEP) has the potential to avert many new HIV infections, yet little is known about how to reach women at high risk for HIV infection and motivate them to initiate PrEP. Clinical trials have succeeded in recruiting at-risk…

Background: Observational and laboratory studies suggest that some hormonal contraceptive methods, particularly intramuscular depot medroxyprogesterone acetate (DMPA-IM), might increase women's susceptibility to HIV acquisition. We aimed to compare DMPA-IM, a copper intrauterine…

Men's relatively low rates of HIV testing has been termed the 'HIV blind spot' and recently declared by UNAIDS as a top priority. This study uses data from five nationally representative Demographic and Health Surveys in Kenya, Malawi, Mozambique, Zambia, and Zimbabwe to explore factors…

USAID’s Office of HIV/AIDS (OHA) and the Center for Innovation and Impact (CII) are excited to announce the launch of “V”, a human-centered design approach to addressing challenges in uptake and adherence for oral PrEP among adolescent girls and young women. “V” is designed to…

We assessed the relationship between distance to clinic and progression through the HIV care cascade. We have two key findings. First, distance matters but only for women. Second, for women, distance affected linkage to care, but was not associated with later transitions in the care cascade. It…

Professor Quarraisha Abdool Karim is one of the world’s leading AIDS researchers and has made pioneering contributions to understanding the HIV epidemic in young people, especially among young women. She joined us for a two-part series to explain her latest research into epidemic hot spots in…

The Partnership for HIV-Free Survival (PHFS) was designed to use basic quality improvement practices to reduce mother-to-child transmission of HIV and increase child survival through improvements in (1) antiretroviral therapy uptake and retention among HIV-positive pregnant women and mothers, (2…

Despite many achievements, stigma, discrimination, gender inequality, violence and other human rights violations continue to make people vulnerable to the epidemic and hinder access to HIV services. AIDS activists and civil society organisations that were critical to successes to date are…

Despite progress in many aspects of the global HIV response, women - particularly adolescent girls and young women - continue to be disproportionately affected by HIV. Women constitute more than half of all people living with HIV. AIDS-related illnesses remain the leading cause of death for…

Despite being designed for autonomous use, research suggests partner approval is often necessary in women's microbicide use. Microbicide study participants have described many ways product use affects relationships, from improving sexual pleasure to increasing harm, including exacerbating…

BACKGROUND: In Mozambique, the widow is traditionally required to undergo a cleansing ritual called pita-kufa, which generally involves…

Project SOAR has synthesized its learnings to-date from integrating a gender lens into its implementation science research. Our gender analysis highlights findings from across studies that are:

Objective: This article provides an overview and interpretation of the performance of the US President’s Emergency Plan for AIDS Relief’s (PEPFAR’s) male circumcision programme which has supported the majority of voluntary medical male circumcisions (VMMCs) performed for HIV…

This photo story, about implementing the CHARISMA intervention pilot in Johannesburg, South Africa, illustrates how the pilot unfolded, starting with CHARISMA lay counselors conducting relationship assessments in 2016 with women using the vaginal dapivirine ring for HIV prevention in the MTN-025…

The International Partnership for Microbicides (IPM) 2017 annual report takes a look at promising woman-centered technologies that could expand women's prevention options and help empower them to protect their sexual and reproductive health on their own terms. Available in …

The Population Council leads Evidence to End FGM/C: Research to Help Girls and Women Thrive—a UKAID-funded research programme to help end female genital…

August 24, 2018

Worldwide, a large proportion of all new HIV infections occur in people under age 25. AIDS is currently the leading cause of death among adolescents in sub-Saharan Africa and the second leading cause of death globally. AIDS-related deaths are declining in every age group except 10–19 years old…

Globally, adolescent girls and young women (AGYW), ages 15–24 years, are disproportionately affected by HIV/AIDS. In 2016, approximately 400,000 of this group were newly HIV-positive. Despite the epidemiological and human rights imperative to support AGYW in remaining AIDS-free, programming to…

End-user input is critical to inform development of multipurpose prevention technology (MPT) products that prevent HIV and pregnancy. The TRIO Study, conducted in Kenya and South Africa, enrolled 277 HIV-negative women aged 18–30 in a randomized cross-over study to use each placebo MPT (daily…

Background
Understanding the absolute and relative risk of human immunodeficiency virus type 1 (HIV) acquisition during pregnancy and the postpartum period can inform HIV prevention strategies for women.

Methods
We used a complementary log-…

A number of antiretroviral HIV prevention products are efficacious in preventing HIV infection. However, the sexual and reproductive health needs of many women extend beyond HIV prevention, and research is ongoing to develop multi‐purpose prevention technologies (MPTs) that offer dual HIV and…

While a considerable amount of information is available on the factors that contribute to HIV risk for adolescent girls and young women (AGYW) in Mozambique, little is known about the characteristics of boys and men with whom AGYW engage in sexual activity and how AGYW form sexual partnerships.…

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HIV acquisition during pregnancy and breastfeeding significantly contributes toward paediatric HIV infection; however, little is known about risk behaviours in HIV-uninfected pregnant and postpartum women. We conducted twenty-six in-depth-interviews between July and December 2016 using a semi-…

Globally, HIV disproportionately affects female sex workers (FSWs) yet HIV treatment coverage is suboptimal. To improve uptake of HIV services by FSWs, it is important to identify potential inequalities in access and use of care and their determinants. Our aim is to investigate HIV treatment…

Universal antiretroviral therapy (ART) for all pregnant/ breastfeeding women living with HIV, known as prevention of mother-to-child transmission of HIV (PMTCT) Option B+ (PMTCTB+), is being scaled up in most countries in Sub-Saharan Africa. In the transition to PMTCTB+, many countries face…

Uganda has experienced cases of tetanus in the safe male circumcision (SMC) program for HIV prevention. Gulu district begun implementation of tetanus toxoid (TT) vaccination of men prior to SMC in 2015. However, there is concern that the introduction of the vaccine in SMC may lead to reduced…

The extraordinary scale-up of antiretroviral therapy (ART) is expected to reduce the rate of new HIV infections at the population level. In this study, we calculated the incidence of HIV for males and females using data from a complete South African population.

The Africa Health Research…