Resource Library

BACKGROUND: Sub-Saharan African correctional facilities concentrate large numbers of people who are living with HIV or at risk for HIV infection. Universal test and treat (UTT) is widely recognized as a promising approach to improve the health of individuals and a population…

BACKGROUND: Self-stigma, also known as internalised stigma, is a global public health threat because it keeps people from accessing HIV and other health services. By hampering HIV testing, treatment and prevention, self-stigma can compromise the sustainability of health…

Significant resources have created strong ‘test and treat’ programs globally. What about those who test HIV negative? How can we strengthen linkage of HIV-negative individuals to prevention programs in ways that work for them? In our recently completed Test-And-Prevent Analysis, the OPTIONS…

Couples HIV testing and counseling (couple counseling) promotes safer sexual behaviors, increases communication between couples, and decreases HIV transmission. However, the impact of couple counseling on social support, critical for persons living with HIV, has not been examined. Ninety couples…

Since rapid cryptococcal antigen lateral flow assays (CrAg LFA) may expedite treatment of HIV-associated cryptococcal infections, we sought to validate clinic-based CrAg LFA testing. Among newly-diagnosed HIV-infected adults in South Africa, a trained nurse performed clinic-based testing of…

BACKGROUND: Community-based GeneXpert MTB/RIF testing may increase detection of prevalent TB in the community and improve rates of TB treatment completion.

METHODS: We conducted a pilot randomized trial to evaluate the impact of GeneXpert screening on a…

Men's relatively low rates of HIV testing has been termed the 'HIV blind spot' and recently declared by UNAIDS as a top priority. This study uses data from five nationally representative Demographic and Health Surveys in Kenya, Malawi, Mozambique, Zambia, and Zimbabwe to explore factors…

RATIONALE: In the context of rapid antiretroviral therapy (ART) rollout and an increasing burden of non-communicable diseases, there are few contemporary data describing the aetiology and outcome of community-acquired pneumonia (CAP) in sub-Saharan Africa.

Community-based HIV testing and counseling (HTC) programs have become an important part of the healthcare system in South Africa and other low- and middle-income countries with a high HIV prevalence and strained primary healthcare system. Current HTC programs excel at identifying people living…

BACKGROUND: Guidelines recommend integrating hypertension screening for HIV-infected adults, but blood pressure measurements may be dynamic around the time of HIV testing.

METHODS: We measured a seated resting blood pressure in adults (>/=18 years)…

BACKGROUND: Suboptimal HIV testing rates through available testing approaches such as HIV counselling and testing have directed research efforts toward recognizing the potential of HIV self-testing as an additional testing method. However, HIV self-testing is not readily…

BACKGROUND: In several subgroups of South Africa, the percentage of HIV-positive individuals aware of their status falls well below the UNAIDS 90% target. This study examined the impact that home-based HIV testing services (HBHTS) had on knowledge of status in a hyperendemic…

Background

Initiation of antiretroviral therapy (ART) following diagnosis of HIV infection at birth is an emerging area of paediatric HIV care. We present outcomes of HIV-infected infants identified at birth at Rahima Moosa Mother and Child Hospital in Johannesburg,…

Age-of-consent laws can be a barrier to adolescents accessing relevant HIV/AIDS services. This study provides new evidence that a lower legal age of consent could address this barrier, especially in countries with more restrictive legislation, and increase HIV testing and counselling uptake. HIV…

For people who may have been exposed to HIV, knowledge is critical to making informed decisions about their future. An HIV test is a serious event with potentially serious outcomes. But no matter the result, the test provides vital information. A negative result is an opportunity to take…

The Southern African HIV Clinicians Society’s biannual conference, held in Johannesburg, South Africa, from 24-27 October 2018, focused on clinical content for HIV and TB health care workers in the region and featured a wide range of topics…

South Africa has implemented a community-based HIV programme (CBHP) in its primary healthcare (PHC) re-engineering strategy that aims to improve public healthcare delivery. This CBHP is delivered by ward-based outreach teams (WBOTs); provision of community HIV services comprises an important…

BACKGROUND: HPTN071 (PopART) is a 3-arm community-randomised study in 21 peri-urban/urban communities in Zambia and the Western Cape of South…

The 2018 International AIDS Conference called attention to men’s low uptake of HIV testing services (HTS) and the need for greater efforts to ensure men know their status and link to treatment if they test positive for HIV. As a first step to better understanding the barriers…

USAID and PEPFAR's approach to pursuing HIV epidemic control is transforming lives and supporting the development of healthy, self-reliant Malawian people. This video demonstrates how partners are collaborating to bring HIV services to hard-to-reach populations, such as fishermen. …

The availability of potent antiretroviral therapy (ART) has transformed the HIV epidemic, changing HIV disease from a fatal illness to a chronic, manageable condition. In higher income countries, life expectancy for people living with HIV(PLWH) has increased substantially, nearing that of the…

HIV testing is free in Malawi, but users may still incur costs that can deter or delay them accessing these services. We sought to identify and quantify these costs among HIV testing service clients in Malawi. We asked residents of communities participating in a cluster randomised trial…

This app provides mobile access to WHO PrEP Implementation Tool (WHO Implementation Tool for Pre-Exposure Prophylaxis of HIV Infection) and was developed to be a “digital pocket reference” available for clinicians and pharmacists. 

The app offers:

This Framework is a practical tool to guide HIV programme managers on how to consider HIV testing and linkage services differently. The structured approach to performing the situation analysis and building HIV testing service delivery models is aimed at helping countries reach the first 90.…

Since WHO published the 2016 ARV guidelines, several studies have evaluated the safety and efficacy of dolutegravir (DTG) during pregnancy and the…

HIV-related stigma, and particularly perceived stigma, has a negative impact across the HIV care continuum. This study adds to our understanding of stigma by assessing how perceived stigma varies from one context to another and how such differences are associated with the location where…