Resource Library

December 5, 2019

Hundreds of thousands of people continue to die from advanced HIV, also known as AIDS, because countries are still ill-equipped to detect and treat people suffering through advanced stages of the disease, according to a new report …

The Southern Africa HIV and AIDS Regional Exchange (SHARE) is pleased to present the latest issue of the research digest. The digest offers article abstracts from peer-reviewed literature related to HIV and AIDS in southern Africa and is designed to keep you in touch with the rapidly expanding…

The U.S. President's Emergency Plan for AIDS Relief (PEPFAR) delivers life-saving services to people affected by the HIV/AIDS epidemic in 36 country and regional programs. Founded in 2003, PEPFAR is the largest investment in combating a single disease by a single country in history. To date,…

Background: Drug resistance is a challenge for the global control of tuberculosis. We examined mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of results from drug susceptibility testing done locally and in a reference…

The Southern Africa HIV and AIDS Regional Exchange (SHARE) is pleased to present the second issue of the project’s research digest. The digest offers article abstracts from peer-reviewed literature related to HIV and AIDS in Southern Africa and is designed to keep you in touch with the rapidly…

Our objective was to evaluate the performance of HIV testing algorithms based on WHO recommendations, using data from specimens collected at six HIV testing and counselling sites in sub-Saharan Africa (Guinea, Conakry; Kitgum and Arua, Uganda; Homa Bay, Kenya; Douala, Cameroun; Baraka,…

Countries in the West and Central African regions struggle to offer quality HIV care at scale, despite HIV prevalence being relatively low. In these challenging operating environments, basic health care needs are multiple, systems are highly fragile and conflict disrupts health care. Médecins…

Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa,…

This report presents progress made after two years of implementation of the ESA Commitment (2013-2015). Significant progress has already been made thanks to concerted action by governments, civil society, and development partners at national and regional level.

The data presented was…

Based on the hypothesis that poor mental health may affect adherence to HIV treatment in newly diagnosed mothers, this study assessed the association between prenatal depression and loss-to-follow-up and uptake of PMTCT services.  At enrollment, 11.8% of study participants reported symptoms of…

Rapid diagnostic tests (RDTs) account for more than two-thirds of malaria diagnoses in Africa. Deletions of the Plasmodium falciparum hrp2 (pfhrp2) gene cause false-negative RDT results and have never been investigated on a national level. Spread of pfhrp2-deleted 

The role of STIs in the transmission dynamics of HIV epidemics is paradoxical and complex. Population-based studies have found that both the prevalence and incidence of HIV were substantially higher among people with STIs. However, randomized trials have found STI treatment to have little to no…

The Southern Africa HIV and AIDS Regional Exchange portal (SHARE - www.hivsharespace.net) is a…

The AIDSFree HIV Testing Services Community of Practice provides a forum to connect with and learn from peers working in HIV testing services around the world. Community members ask questions, share lessons learned, access the latest literature and news in HIV testing, and learn from experts—…

Fact sheet N°104

Key facts:
  • Tuberculosis (TB) is a top infectious disease killer worldwide.
  • In 2014, 9.6 million people fell ill with TB and 1.5 million died from the disease.
  • Over 95% of TB deaths occur in low- and middle-income countries,…

This document includes:

  • A Strategic Development Summary (SDS) narrative communicating the epidemiologic and country/regional context; methods used for programmatic design; findings of integrated data analysis; and strategic direction for the investments and programs. 
  •  …

To improve tuberculosis (TB) diagnosis, many national TB programmes have committed to deploying Xpert® MTB/RIF. Implementation of this relatively new technology has suffered from a lack of comprehensive technical assistance, however, including the formulation of policies and plans to address…

The Primary Health Care Performance Initiative (PHCPI) is a new partnership that brings together country policymakers, health system managers, practitioners, advocates and other development partners to catalyze improvements in primary health care (PHC) in low- and middle-income countries through…

In 2000, malaria was identified as one of the biggest impediments to global development and selected as a critical global target of the Millennium Development Goals (MDGs). Target 6c aimed to halt and begin to reverse the incidence of malaria by 2015.

This report summarizes the remarkable…

Tuberculosis (TB) remains one of the world’s deadliest communicable diseases. In 2013, an estimated nine million people developed TB and 1.5 million died from the disease. Africa accounts for 25% of the world’s TB cases, with the highest rates of cases and deaths relative to population.…

Thembalethu DevelopmentThembalethu Development is a non-profit organization founded in 2002 that works in several South African…

The U.S. Government is committed and working toward the goal of Ending Preventable Child and Maternal Deaths (EPCMD) in a generation. In June of 2014, the U.S. Agency for International Development (USAID) released a vision for maternal health,…

The Secretariat of the Joint United Nations Programme on HIV/AIDS (UNAIDS) has undertaken qualitative rapid assessments of gender- related and cultural barriers to access HIV services in partnership with women living with HIV at six sites in the Democratic Republic of the Congo, Ethiopia, India…

The Joint United Nations Programme on HIV/AIDS (UNAIDS) recently updated its global targets for antiretroviral therapy (ART) coverage for HIV-positive persons under which 90 % of HIV-positive people are tested, 90 % of those are on ART, and 90 % of those achieve viral suppression. Treatment…

Donor funding for HIV programs has flattened out in recent years, which limits the ability of HIV programs worldwide to achieve universal access and sustain current progress. This study examines alternative mechanisms for resource mobilization.

The Xpert MTB/RIF assay is an accurate test for the diagnosis of tuberculosis when an adequate sputum sample can be obtained; even in smear-negative tuberculosis the sensitivity is about 67%. Although the assay turnaround time is under 2 h, depending on the health-care setting, time to…

Among all health workers, nurses experience the most needle stick injuries, which expose them to over 20 blood borne pathogens, thevmost common and serious being HIV and hepatitis B and C. A study conducted in Uganda showed that up to 57% of nurses and midwives had experienced at least one…