Resource Library

Background: Antiretroviral treatment (ART) reduces HIV infectiousness but the effect of early ART on sexual behaviour is unclear.

Methods: We assessed, within the START randomized trial that enrolled HIV-positive adults with CD4+ cell count greater than…

BACKGROUND: Gauteng Province has the second lowest tuberculosis (TB) incidence rate in South Africa but the greatest proportion of TB/HIV co-…

BACKGROUND: Women account for 56% of new HIV infections in sub-Saharan Africa. Multipurpose Prevention Technologies (MPTs) are promising interventions because they combine HIV prevention with a less stigmatizing indication, such as pregnancy…

Background: The Eastern Cape province of South Africa has one of the highest burdens of HIV in the world. Emergency Departments (EDs) can serve as optimal clinical sites for the identification of new HIV infections and entry into care. We sought to determine the current burden…

Broadly neutralizing antibodies (bnAbs) are currently under investigation as a therapy for HIV-1 infection and recent clinical trials have shown prolonged viral suppression by bnAbs during antiretroviral treatment interruption. Interestingly, these bnAbs also showed the ability to activate the…

BACKGROUND: Pregnant and post-partum adolescent girls and young women (AGYW) living with HIV in sub-Saharan Africa experience inferior outcomes along the prevention of mother-to-child transmission of HIV (PMTCT) cascade compared to their adult counterparts. Yet, despite this…

BACKGROUND: Poor retention in the prevention of women in prevention of vertical transmission programs remains a formidable common setback in elimination of HIV/AIDS. It creates new problems such as poor health outcomes and increased incidence of vertical transmission of HIV.…

More adolescents and young adults living with HIV are surviving into adulthood. As a result they must transition from pediatric health services to HIV self-management and adult care. This change is particularly important as many young people have poor adherence to treatment, leading to low rates…

Background: The level of evidence for HIV transmission risk through condomless sex in serodifferent gay couples with the HIV-positive partner taking virally suppressive antiretroviral therapy (ART) is limited compared with the evidence available for transmission risk in…

Female adolescents from socioeconomically underserved communities in Cape Town, South Africa, who have dropped out of school, use substances, and engage in risky sex behaviour are at risk of HIV. Tailored gender-focused HIV behavioural interventions for this key population are needed to mitigate…

In sub-Saharan Africa, harmful alcohol use among male drinkers is high and has deleterious consequences on adherence to antiretroviral therapy (ART), HIV clinical outcomes, and couple relationship dynamics. We conducted in-depth qualitative interviews with 25 Malawian couples on ART to…

USAID’s Office of HIV/AIDS (OHA) and the Center for Innovation and Impact (CII) are excited to announce the launch of “V”, a human-centered design approach to addressing challenges in uptake and adherence for oral PrEP among adolescent girls and young women. “V” is designed to…

INTRODUCTION: Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test HIV positive will be referred to start antiretroviral therapy (ART). Although there is strong evidence from clinical…

SheConquers, the South African national campaign that aims to improve the lives of adolescent girls and young women and their male peers in South Africa, held a 2-day workshop that accommodated 27 young people representing all 9 provinces from South Africa.

The objective of the meeting…

MEASURE Evaluation’s PLACE method builds local capacity to find HIV-positive people who are not on treatment, who may not know their HIV status, and who therefore are at risk of infecting others. The HIV/AIDS epidemic is often concentrated among “key populations”—men who have sex…

Background: There has been a notable expansion in routine health care in sub-Saharan Africa. While heath care is nominally free in many contexts, the time required to access services reflects an opportunity cost that may be substantial and highly gendered, reflecting the…

The 2018 International AIDS Conference called attention to men’s low uptake of HIV testing services (HTS) and the need for greater efforts to ensure men know their status and link to treatment if they test positive for HIV. As a first step to better understanding the barriers…

Project SOAR has synthesized its learnings to-date from integrating a gender lens into its implementation science research. Our gender analysis highlights findings from across studies that are:

Background: The recent scale-up of prevention of mother-to-child transmission of HIV (PMTCT) services has rapidly accelerated antiretroviral therapy (ART) uptake among pregnant and postpartum women in sub-Saharan Africa. The Mother and Infant Retention for Health (MIR4Health)…

Globally, adolescent girls and young women (AGYW), ages 15–24 years, are disproportionately affected by HIV/AIDS. In 2016, approximately 400,000 of this group were newly HIV-positive. Despite the epidemiological and human rights imperative to support AGYW in remaining AIDS-free, programming to…

Jhpiego’s Gender Service Delivery Standards are a tool to assess and improve the quality of health facilities' provision of gender-sensitive, respectful care. 

The USAID- and PEPFAR-supported LINKAGES project is excited to announce the arrival of a new…

This Framework draws purposeful attention to men who have sex with men, transgender people, people who inject drugs and sex workers. The framework outlines the methodology for identifying specific challenges, deciding what DSD models may solve these challenges and how to systematically adapt or…

While a considerable amount of information is available on the factors that contribute to HIV risk for adolescent girls and young women (AGYW) in Mozambique, little is known about the characteristics of boys and men with whom AGYW engage in sexual activity and how AGYW form sexual partnerships.…

The LINKAGES project quarterly research digest comprises article abstracts from the peer-reviewed literature related to HIV and key populations in Africa, Asia and Pacific, Eastern Europe, Latin America, the Caribbean, and the Middle East.

This resource keeps you in touch with the…

HIV in Mauritius is in a concentrated phase. Most HIV infection is among key populations (KPs) including female sex workers (FSW), people who inject drugs (PWID), men who have sex with men (MSM), and transgender sex workers (TGSW). The objective of this research was to use geographical mapping…

 

INTRODUCTION:
Significant progress has been made with respect to the initiation of children on antiretroviral therapy (ART) in Southern Africa, including Swaziland, however, retention of these children in care poses a major challenge. The aim of the study was to…

This case study is about the Consortium of MSM and Transgender Networks (the Consortium), a groundbreaking collaboration of global and regional networks by and for men who have sex with men (MSM) and transgender people. It describes the Consortium’s achievements, good practices and lessons…