Resource Library

Introduction

In Kenya, men who have sex with men (MSM) are increasingly using virtual sites, including web‐based apps, to meet sex partners. We examined HIV testing, HIV prevalence, awareness of HIV‐positive status and linkage to antiretroviral therapy (…

When sick children arrive at primary health care (PHC) facilities, it is critical that they are appropriately screened, diagnosed, and managed, and if needed, referred to urgent care without delay. Clinical signs alone do not detect all indicators of severe illness in children. In order for…

Introduction

As adolescents and young people living with HIV (AYLH) age, they face a “transition cascade,” a series of steps associated with transitions in their care as they become responsible for their own healthcare. In high‐income countries, this usually includes…

Thirty years into the HIV response, there is growing recognition that engaging men will be key to reaching the global UNAIDS fast‐track targets of 90‐90‐90 by the end of 2020 – whereby 90% of people living with HIV know their status, 90% of those who know they are positive are on antiretroviral…

The National Strategic Plan for HIV, TB and STIs (NSP) 2017-2022 Mid Term Review (MTR) was an in-depth analysis of the NSP implementation, with the aim to illustrate progress made towards reaching the NSP targets across the eight NSP goals. The review focused on the first half of the NSP term (…

According to the recent Evidence for Contraceptive Options and HIV Outcomes Study (ECHO) (Box 1) (1), the incidence of HIV infection and other sexually transmitted infections (STIs) remains high among adolescent girls and women in parts of East and Southern Africa. But, there and elsewhere,…

The rise in the global female prison population, women’s unique vulnerabilities to HIV infection and insufficient provision and inequitable access to HIV services places the prevention of mother-to-child transmission (PMTCT) in prisons high on the agenda of HIV prevention among key populations…

This retrospective evaluation sought to understand the long-term impact of an extracurricular, school-based HIV prevention programme that leveraged off a mass media television "edutainment" series in South Africa. The study looked at young women who had taken part in the programme because of its…

Background
There has been a heightened emphasis on prioritizing data to inform evidence-based HIV responses, including data focused on both defining the content and scale of HIV programs in response to evidence-based need. Consequently, population size estimation (PSE)…

Background: Antiretroviral treatment (ART) reduces HIV infectiousness but the effect of early ART on sexual behaviour is unclear.

Methods: We assessed, within the START randomized trial that enrolled HIV-positive adults with CD4+ cell count greater than…

INTRODUCTION: Adolescent girls and young women aged 15 to 24 years have some of the highest HIV incidence rates globally, with girls two to four times more likely to be living with HIV than their male peers. High levels of intimate partner…

BACKGROUND AND OBJECTIVES: This study aimed to assess the level of HIV disclosure to children in sub-Saharan Africa as it relates to prevalence of disclosure, barriers, merits and demerits, timing of disclosure, and factors…

BACKGROUND: Most countries have formally adopted the World Health Organization's 2015 recommendation of universal HIV treatment ("treat all"). However, there are few rigorous assessments of the real-world impact of treat all policies on antiretroviral treatment (ART…

BACKGROUND: The NEVEREST-3 (South Africa) and MONOD-ANRS-12206 (Cote d'Ivoire, Burkina Faso) randomized trials found that switching to efavirenz (…

PURPOSE: An intervention including business training and health education was implemented in Mozambique, where girls are at elevated risk for…

BACKGROUND: Little is known about contextual factors that predict long-term mortality following HIV testing in resource-limited settings. We…

BACKGROUND: Gauteng Province has the second lowest tuberculosis (TB) incidence rate in South Africa but the greatest proportion of TB/HIV co-…

One-C is a community-based program that seeks to increase utilization of HIV services, improve linkages to services at the community level, and encourage the adoption of HIV risk reduction behaviors. Find out about the quantitative and qualitative results emerging from SOAR’s…

BACKGROUND: The Human Immunodeficiency Virus (HIV) epidemic is growing rapidly among South African adolescents and young adults (AYA). Although HIV counselling and testing, HIV prevention and treatment options are widely available, many AYA…

Hear Dr. Vincent Tukei of Elizabeth Glaser Pediatric AIDS Foundation discuss SOAR findings on adverse pregnancy outcomes among HIV-positive women in Lesotho during an interview with…

August 27, 2019

Oral pre-exposure prophylaxis (PrEP) is a new HIV prevention method that offers more than 90 percent protection when taken correctly. The OPTIONS Consortium, in collaboration…

Background: The Eastern Cape province of South Africa has one of the highest burdens of HIV in the world. Emergency Departments (EDs) can serve as optimal clinical sites for the identification of new HIV infections and entry into care. We sought to determine the current burden…

Broadly neutralizing antibodies (bnAbs) are currently under investigation as a therapy for HIV-1 infection and recent clinical trials have shown prolonged viral suppression by bnAbs during antiretroviral treatment interruption. Interestingly, these bnAbs also showed the ability to activate the…

Background: HIV acquisition remains high among adolescent girls and young women (AGYW, aged 15–24 years) in sub-Saharan Africa. We aimed to estimate prevalence and incidence of HIV in AGYW and to identify correlates of HIV infection by using data from the Lesotho Population-…

Training Curriculum for Adolescent Girls and Young Women

The OPTIONS Consortium, in collaboration with Collective Action, has developed an HIV Prevention Ambassador…

BACKGROUND: Pregnant and post-partum adolescent girls and young women (AGYW) living with HIV in sub-Saharan Africa experience inferior outcomes along the prevention of mother-to-child transmission of HIV (PMTCT) cascade compared to their adult counterparts. Yet, despite this…

BACKGROUND: Poor retention in the prevention of women in prevention of vertical transmission programs remains a formidable common setback in elimination of HIV/AIDS. It creates new problems such as poor health outcomes and increased incidence of vertical transmission of HIV.…

BACKGROUND: The Prevention of Mother to Child Transmission (PMTCT) of HIV programme in Zimbabwe has had remarkable success despite the country's economic challenges. The aim of this study was to explore the challenges faced by breastfeeding mothers on the PMTCT programme.