Resource Library

BACKGROUND: Gauteng Province has the second lowest tuberculosis (TB) incidence rate in South Africa but the greatest proportion of TB/HIV co-…

August 27, 2019

Oral pre-exposure prophylaxis (PrEP) is a new HIV prevention method that offers more than 90 percent protection when taken correctly. The OPTIONS Consortium, in collaboration…

Background: The Eastern Cape province of South Africa has one of the highest burdens of HIV in the world. Emergency Departments (EDs) can serve as optimal clinical sites for the identification of new HIV infections and entry into care. We sought to determine the current burden…

Broadly neutralizing antibodies (bnAbs) are currently under investigation as a therapy for HIV-1 infection and recent clinical trials have shown prolonged viral suppression by bnAbs during antiretroviral treatment interruption. Interestingly, these bnAbs also showed the ability to activate the…

Training Curriculum for Adolescent Girls and Young Women

The OPTIONS Consortium, in collaboration with Collective Action, has developed an HIV Prevention Ambassador…

BACKGROUND: Pregnant and post-partum adolescent girls and young women (AGYW) living with HIV in sub-Saharan Africa experience inferior outcomes along the prevention of mother-to-child transmission of HIV (PMTCT) cascade compared to their adult counterparts. Yet, despite this…

BACKGROUND: Poor retention in the prevention of women in prevention of vertical transmission programs remains a formidable common setback in elimination of HIV/AIDS. It creates new problems such as poor health outcomes and increased incidence of vertical transmission of HIV.…

As South Africa seeks to implement national policies on school-based health education and services it is important that the evidence and experiences of existing school health programs be accessible to service providers and role-players. It is for this reason that Médecins Sans Frontières/Doctors…

More adolescents and young adults living with HIV are surviving into adulthood. As a result they must transition from pediatric health services to HIV self-management and adult care. This change is particularly important as many young people have poor adherence to treatment, leading to low rates…

This research report documents the multiple benefits of meaningful youth participation and leadership in sexual health and rights (SRHR) programs. It synthesizes global evidence from the field on how to foster authentic youth engagement, the impacts that result, and recommendations that can…

In sub-Saharan Africa, harmful alcohol use among male drinkers is high and has deleterious consequences on adherence to antiretroviral therapy (ART), HIV clinical outcomes, and couple relationship dynamics. We conducted in-depth qualitative interviews with 25 Malawian couples on ART to…

OBJECTIVES: Syndromic management of sexually transmitted infections (STIs) omits asymptomatic infections, particularly among women. Accurate point-of-care assays may improve STI care in low- and middle-income countries (LMICs). We aimed to evaluate the diagnostic performance of…

Tsogolo la Thanzi (TLT) was designed to study how young adults navigate sexual relationships and childbearing during a generalized HIV epidemic. TLT began in 2009 with a population-representative sample of 1,505 women and 574 men between the ages of 15 and 25 living in Balaka, southern Malawi,…

INTRODUCTION: Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test HIV positive will be referred to start antiretroviral therapy (ART). Although there is strong evidence from clinical…

The International Partnership for Microbicides (IPM) 2017 annual report takes a look at promising woman-centered technologies that could expand women's prevention options and help empower them to protect their sexual and reproductive health on their own terms. Available in …

The Population Council leads Evidence to End FGM/C: Research to Help Girls and Women Thrive—a UKAID-funded research programme to help end female genital…

Background: The recent scale-up of prevention of mother-to-child transmission of HIV (PMTCT) services has rapidly accelerated antiretroviral therapy (ART) uptake among pregnant and postpartum women in sub-Saharan Africa. The Mother and Infant Retention for Health (MIR4Health)…

BACKGROUND:

Oral pre-exposure prophylaxis (PrEP) has the potential to reduce HIV acquisition among adolescent girls and young women (AGYW) in sub-Saharan Africa. However, health care providers' (HCPs) perspectives and interactions with potential clients can substantially…

Despite declining trends, maternal mortality remains an important public health issue in Mozambique. The delays to reach an appropriate health facility and receive care faced by woman with pregnancy-related complications play an important role in the occurrence of these deaths. This study aims…

 

INTRODUCTION:
Significant progress has been made with respect to the initiation of children on antiretroviral therapy (ART) in Southern Africa, including Swaziland, however, retention of these children in care poses a major challenge. The aim of the study was to…

The Guttmacher-Lancet Commission’s report lays out the scope of the unfinished sexual and reproductive health and rights (SRHR) agenda; articulates a bold and evidence-based vision for SRHR that is grounded in human rights; provides an integrated, new definition of SRHR to guide this…

The Sustainable Development Goals (SDGs) present a groundbreaking global development agenda to protect the most vulnerable. Adolescents living with HIV in Sub‐Saharan Africa continue to experience extreme health vulnerabilities, but we know little about the impacts of SDG‐aligned provisions on…

Injectable contraceptives are popular in sub-Saharan Africa but have high discontinuation rates due partly to the need for provider-administered re-injection. We compared continuation rates of women who self-injected subcutaneous depot medroxyprogesterone acetate (DMPA-SC) and women who received…

Many of the participants for Interagency Gender Working Group (IGWG) trainings come from a technical perspective. Whereas they might find theory interesting, they are most engaged when they have the opportunity to directly apply new knowledge to their current work. Therefore, the activities in…

Adolescent girls in sub-Saharan Africa are disproportionately affected by HIV due to a range of social and structural factors. As they transition to adulthood, they are recipients of increasing blame for HIV infection and 'improper' sex, as well as increasing scrutiny, restrictions and…

February 19, 2018

The Prevention Access Campaign is a health equity initiative to end the dual epidemics of HIV and HIV-related stigma by empowering people with and…

Although several studies have explored factors associated with loss to follow-up (LTFU) from HIV care, there remains a gap in understanding how these factors vary by setting, volume of patient and patients’ demographic and clinical characteristics. We determined rates and factors associated with…

Communities in South Africa’s informal settlements consist of ad-hoc and improvised housing whose residents seek opportunities for employment in the surrounding area. Since the settlements are unplanned, they are often underserved by municipal services, are under-represented politically, and…