Resource Library

BACKGROUND: Gauteng Province has the second lowest tuberculosis (TB) incidence rate in South Africa but the greatest proportion of TB/HIV co-…

Early infant diagnosis (EID) of HIV provides an opportunity for early HIV detection and access to appropriate antiretroviral treatment (ART). Dried Blood Spot (DBS) samples are used for EID of exposed infants, born to HIV-positive mothers. However, DBS rejection rates in…

Getting good information about how many people are in treatment for HIV/AIDS is important for any country. In Burundi, a recent study assessed available client data at a sample of facilities providing antiretroviral therapy. The study used the Lot Quality Assurance Sampling (…

Tools and methods for assessing data quality have significantly advanced, in part by the need for good HIV/AIDS data to inform programs. Most of the existing tools, however, focus on aggregate data at subnational levels. Very few tools measure the quality of data at the primary source–…

August 27, 2019

Oral pre-exposure prophylaxis (PrEP) is a new HIV prevention method that offers more than 90 percent protection when taken correctly. The OPTIONS Consortium, in collaboration…

On August 14 MEASURE Evaluation hosted a webinar focused on strategic information and HIV/AIDS and strengthening health information systems contributes to epidemic control. This includes (1) strengthening routine health information systems; (2) improved routine data quality for continuous…

Training Curriculum for Adolescent Girls and Young Women

The OPTIONS Consortium, in collaboration with Collective Action, has developed an HIV Prevention Ambassador…

HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has demonstrated that there is substantial local variation in the prevalence of HIV; however, subnational variation has not been investigated at a high spatial resolution across the continent. Here we explore…

Johanna Theunissen, Communications Officer at Technical Support to PEPFAR Programs (TSP), Baylor College of Medicine Children’s Foundation Malawi, presented at the 2019 South African AIDS Conference (SA AIDS 2019) on the innovative use of technology through SHARE's online platform and social…

As South Africa seeks to implement national policies on school-based health education and services it is important that the evidence and experiences of existing school health programs be accessible to service providers and role-players. It is for this reason that Médecins Sans Frontières/Doctors…

June 13, 2019

The Evidence for Contraceptive Options and HIV Outcomes (ECHO) Study is an open-label randomised clinical trial comparing three highly effective, reversible methods of contraception — a progestogen-only injectable called depot-medroxyprogesterone acetate (DMPA), a levonorgestrel implant and the…

This research report documents the multiple benefits of meaningful youth participation and leadership in sexual health and rights (SRHR) programs. It synthesizes global evidence from the field on how to foster authentic youth engagement, the impacts that result, and recommendations that can…

Background: The level of evidence for HIV transmission risk through condomless sex in serodifferent gay couples with the HIV-positive partner taking virally suppressive antiretroviral therapy (ART) is limited compared with the evidence available for transmission risk in…

OBJECTIVES: The aim of the study was to investigate the extent of and factors associated with incorrect dosing of antiretroviral therapy (ART) in HIV-infected children in Harare, Zimbabwe.

METHODS: All children aged 0-10 years and children aged 11-17…

Antimicrobial drug resistance is a serious health hazard driven by overuse. Administration of antimicrobial drugs to HIV-exposed, uninfected infants, a population that is growing and at high risk for infection, is poorly studied. We therefore analyzed factors associated with antibacterial drug…

OBJECTIVES: Syndromic management of sexually transmitted infections (STIs) omits asymptomatic infections, particularly among women. Accurate point-of-care assays may improve STI care in low- and middle-income countries (LMICs). We aimed to evaluate the diagnostic performance of…

INTRODUCTION: Treat-all is being implemented in several African settings, in accordance with 2015 World Health Organisation guidelines. The factors known to undermine adherence to antiretroviral therapy (ART) may change in the context of Treat-all, where people living with HIV (…

BACKGROUND: In several subgroups of South Africa, the percentage of HIV-positive individuals aware of their status falls well below the UNAIDS 90% target. This study examined the impact that home-based HIV testing services (HBHTS) had on knowledge of status in a hyperendemic…

In East and Southern Africa, where 5% to 10% have chronic hepatitis B virus (HBV) infection, incidence of human immunodeficiency virus (HIV) infection remains unacceptably high. This introduces challenges and opportunities for implementation of HBV care and treatment. We now describe new HIV…

Tsogolo la Thanzi (TLT) was designed to study how young adults navigate sexual relationships and childbearing during a generalized HIV epidemic. TLT began in 2009 with a population-representative sample of 1,505 women and 574 men between the ages of 15 and 25 living in Balaka, southern Malawi,…

TB Data, Impact Assessment and Communications Hub (TB DIAH) is a new project that just launched a web-based, interactive data platform for global tuberculosis (TB) data users. TB DIAH is associated with the Global Accelerator to End TB, USAID’s new business model to focus on…

The U.S. President's Emergency Plan for AIDS Relief (PEPFAR) delivers life-saving services to people affected by the HIV/AIDS epidemic in 36 country and regional programs. Founded in 2003, PEPFAR is the largest investment in combating a single disease by a single country in history. To date,…

Information from community-based health programs is important for understanding what HIV programs are doing to test, treat, and retain in care people who are living with HIV. However, until now there has been no centralized registry of community-based indicators that would allow programs to…

February 5, 2019

The PrEP Costing Guidelines provide a framework for estimating the cost of providing pre-exposure prophylaxis (PrEP), which is the use of antiretroviral (ARV) drugs for preventing the acquisition of HIV infection. They are intended to provide a PrEP-specific resource for costing that could be…

As part of its Monitoring, Evaluation, and Reporting (MER) guidance, the United States President’s Emergency Plan for AIDS Relief (PEPFAR) released Version 2.3 in September 2018, which includes revised indicators for orphans and vulnerable children (OVC) programs. These indicators are intended…

With funding from PEPFAR, the Human Resources for Health in 2030 (HRH2030) has developed, piloted, and field-tested a tool to help health facility staff and district health management teams optimize their health workforce for the roll-out of “Test and Start” utilizing …

MEASURE Evaluation’s PLACE method builds local capacity to find HIV-positive people who are not on treatment, who may not know their HIV status, and who therefore are at risk of infecting others. The HIV/AIDS epidemic is often concentrated among “key populations”—men who have sex…