Resource Library

Objective 

We used screening data and routine clinic records for intervention arm patients in the Simplified Algorithm for Treatment Eligibility (SLATE) trials to describe the prevalence of tuberculosis (TB) symptoms, diagnosis and treatment among people living with HIV…

Recognizing the urgent need to advance the COVID-19 pandemic response, the IAS COVID-19 Conference: Prevention will feature the latest in prevention related science, policy and practice. The conference will take place virtually on Tuesday, 2 February 2021 – and will include…

Background: 

A strategy of pre-exposure prophylaxis (PrEP) transitioning to treatment as prevention is highly efficacious and cost effective for prevention of HIV transmission within HIV serodiscordant couples. We assessed whether couples in Kenya and Uganda who adopted…

As the gap to reaching targets of controlling and eliminating the HIV pandemic closes, the difficulty to achieve them increases. Achieving aggressive treatment targets will require continued innovation of personalized and differentiated care models, and the proliferation data-driven approaches…

Adolescents are developmentally at a difficult crossroads, which makes it challenging to attract and sustain adolescents’ focus on maintaining their health. Every effort must be made to engage and retain adolescents in care so they can improve and maintain their health for the long term.

Introduction

Men who have sex with men (MSM) and transgender women (TGW) are at increased risk for acquiring HIV, but there are limited HIV incidence data for these key populations in Africa. Understanding HIV prevalence and incidence provides important…

Introduction

Some observational data suggest that the progestogen injectable contraceptive depot medroxyprogesterone acetate (DMPA) may increase a woman’s risk of HIV acquisition but a randomized clinical trial did not find a statistically significant…

South Africa is committed to attaining the UNAIDS 909090 targets to control the HIV epidemic through quality comprehensive health services and use of highly effective antiretroviral treatment (ART). The principal goal of ART is to attain and maintain viral suppression, which will decrease…

Recent developments in health practices that were once in the full control of healthcare professionals and can now be safely self-administered have created a shift in thinking about how individuals engage in self-care. New commodities and drug regimens for self-management and self-testing,…

In 2016, the United Nations General Assembly’s Political Declaration on Ending AIDS committed countries to the 90–90–90 targets, which aim to bring HIV testing and treatment to the vast majority of people living with HIV by the end of 2020 and to reduce the amount of HIV in their bodies to…

September 22, 2020

What is an Ideal Clinic?

An Ideal Clinic is defined as a clinic with good infrastructure, adequate staff, adequate medicine and supplies, good administrative processes, and sufficient adequate bulk supplies. It uses applicable clinical policies, protocols and guidelines…

Global action to combat HIV/AIDS has had an immense impact in the African Region. By the end of 2017, 15.3 million people living with HIV (PLHIV) in the African Region were accessing life-saving antiretroviral drugs (ARVs), representing 70% of the 21.7 million people accessing antiretrovirals (…

Background: 

Undetermined attrition prohibits full understanding of the coverage and effectiveness of HIV programs. Outcomes following loss to follow-up (LTFU) among antiretroviral therapy (ART) patients may differ according to their reasons for ART initiation.

Background

HIV-1 risk scoring tools could help target provision of prevention modalities such as pre-exposure prophylaxis. Recent research suggests that risk scores for women aged 18–45 may not predict risk well among young women aged 18–24. We evaluated the predictive…

The COVID-19 pandemic has exposed the inadequacy of investments in public health, the persistence of profound economic and social inequalities and the fragility of many key global systems and approaches.

Given the epic dimensions of the emergency, the world needs unity and solidarity—led…

Tuberculosis (TB) is the leading infectious cause of death among people living with HIV, causing one third of AIDS-related deaths globally. The concerning number of missing TB cases, ongoing high TB mortality, slow reduction in TB incidence, and limited uptake of TB preventive treatment among…

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Introduction

Despite existing health strategies and guidelines developed to counteract the problem of mother-to-child HIV transmission, it seems that only a certain number of HIV-exposed children aged under five years are managed properly. Poor implementation of…

Introduction: 

In South Africa, evidence shows high HIV prevalence in older populations, with sexual behavior consistent with high HIV acquisition and transmission risk. However, there is a dearth of evidence on older people's HIV incidence.

Methods: …

On July 29, AVAC held a webinar Understanding the EMA Opinion: Next Steps for Dapivirine Vaginal Ring for advocates to learn about next steps on the regulatory process and implications for rollout from advocates, International Partnership for…

Join this live discussion in which the expert panel explores the latest issues relating to HIV care through cases and expert dialogue followed by dedicated time to answer your questions. Topics covered will focus on key areas of HIV management, including optimal use of newer antiretroviral…

Background

The healthcare workforce in high tuberculosis burden countries such as South Africa is at elevated risk of tuberculosis infection and disease with adverse consequences for their well-being and productivity. Despite the availability of international guidelines…

Despite the body of evidence on heterosexual men’s inequitable access to HIV prevention, testing and antiretroviral therapy (ART) [1, …

Introduction

In Kenya, men who have sex with men (MSM) are increasingly using virtual sites, including web‐based apps, to meet sex partners. We examined HIV testing, HIV prevalence, awareness of HIV‐positive status and linkage to antiretroviral therapy (…

Little was known of SARS-CoV-2 a few months ago. However, since then this highly-contagious virus has spread worldwide and has created enormous turmoil all around the world. It has caused major devastation to health, economies, education and has percolated through almost all aspects of daily…

Introduction

People living with HIV (PLWH) are mainly African or Asian, the majority female. In contrast, pharmaceutical companies typically conduct phase 3 regulatory randomised controlled trials (RCTs) in high-income countries (HICs), where PLWH are mainly white males…

Introduction

In South Africa, HIV‐infected men are less likely than women to test and know their status (the first UNAIDS “90‐90‐90” target), and men have worse outcomes across the HIV care cascade. HIV self‐testing (HIVST) may address this testing disparity but…