Resource Library

The rise in the global female prison population, women’s unique vulnerabilities to HIV infection and insufficient provision and inequitable access to HIV services places the prevention of mother-to-child transmission (PMTCT) in prisons high on the agenda of HIV prevention among key populations…

This retrospective evaluation sought to understand the long-term impact of an extracurricular, school-based HIV prevention programme that leveraged off a mass media television "edutainment" series in South Africa. The study looked at young women who had taken part in the programme because of its…

This guide and toolkit is designed to help governments, civil society organizations (CSOs), and other partners implement and monitor programs for HIV prevention, diagnosis, care, treatment, and viral load testing with key populations (KPs)—sex workers (SWs), gay men and other men who have sex…

Restrictions in movement, social isolation and increased socioeconomic pressures around the world have led to an increase in violence against women and girls since the start of the COVID-19 pandemic, according to UNAIDS. In South Africa, Sonke Gender Justice highlighted that 2,230 gender-based…

This edition of HIV Nursing Matters introduces one of the most exciting and highly anticipated antiretroviral (ARV) drugs to enter the HIV treatment space. Dolutegravir (DTG) – a drug with low cost, convenient dosing schedule, high potency, rapid virucidal activity, low toxicity, high genetic…

Selling sex has been illegal in South Africa since at least the early 1900s and buying sex was criminalised in 2007. South African laws also prohibit other aspects of sex work, including running or owning a brothel, living off the earnings of “prostitution,” and enticing a woman into “…

Background
There has been a heightened emphasis on prioritizing data to inform evidence-based HIV responses, including data focused on both defining the content and scale of HIV programs in response to evidence-based need. Consequently, population size estimation (PSE)…

COVID-19 is a serious disease and all people living with HIV should take all recommended preventive measures to minimize exposure to, and prevent infection by, the virus that causes COVID-19. As in the general population, older people living with HIV or people living with HIV with heart or lung…

Right now, we are facing an unpredictable and highly dynamic situation as a global community. However, as we have seen from the solidarity, support and power of communities in the HIV epidemic and already in communities responding to the COVID-19 pandemic…

As COVID-19 disrupts health systems and impacts human health globally, it is crucial to protect those most affected by COVID-19, sustain gains made to address other infectious diseases, and maintain people’s access to life-saving health services. One of the most prominent priorities during the…

This 22nd edition of the South African Health Review (SAHR) is offered in memory of Health Systems Trust board member, and health activist extraordinaire, Professor David Sanders. 

The purpose of the SAHR has always been to analyse and assess progress and challenges in key areas of the…

Boost is a mobile phone app and website designed and developed in collaboration with community health workers and peer educators in southern Africa. Boost provides easy, up-to-date, visual and interactive materials on HIV and sexual health. Boost is:

  • Data light
  • Free to…

Background: Efficient and scalable models for HIV treatment are needed to maximize health outcomes with available resources. By adapting services to client needs, differentiated antiretroviral therapy (DART) has the potential to use resources more efficiently. We conducted a…

Background: Antiretroviral treatment (ART) reduces HIV infectiousness but the effect of early ART on sexual behaviour is unclear.

Methods: We assessed, within the START randomized trial that enrolled HIV-positive adults with CD4+ cell count greater than…

INTRODUCTION: Adolescent girls and young women aged 15 to 24 years have some of the highest HIV incidence rates globally, with girls two to four times more likely to be living with HIV than their male peers. High levels of intimate partner…

This article presents findings from implementation and scale-up of HIV self-testing program for female sex workers in Malawi and Zimbabwe from 2013-2018. It concludes that involving female sex workers in planning and ongoing implementation of HIV self-testing is essential, along with strategies…

BACKGROUND AND OBJECTIVES: This study aimed to assess the level of HIV disclosure to children in sub-Saharan Africa as it relates to prevalence of disclosure, barriers, merits and demerits, timing of disclosure, and factors…

BACKGROUND: Most countries have formally adopted the World Health Organization's 2015 recommendation of universal HIV treatment ("treat all"). However, there are few rigorous assessments of the real-world impact of treat all policies on antiretroviral treatment (ART…

BACKGROUND: The NEVEREST-3 (South Africa) and MONOD-ANRS-12206 (Cote d'Ivoire, Burkina Faso) randomized trials found that switching to efavirenz (…

There is a need for a culturally adapted, evidence-based, psychotherapy treatment that is effective, acceptable, and feasible for integration into primary care in South Africa. This qualitative study used exit interviews to…

INTRODUCTION: Tuberculosis (TB) continues to be a leading cause of death in Sub-Saharan Africa, including Mozambique. While diagnostic methods and…

PURPOSE: An intervention including business training and health education was implemented in Mozambique, where girls are at elevated risk for…

BACKGROUND: Little is known about contextual factors that predict long-term mortality following HIV testing in resource-limited settings. We…

BACKGROUND: Gauteng Province has the second lowest tuberculosis (TB) incidence rate in South Africa but the greatest proportion of TB/HIV co-…

One-C is a community-based program that seeks to increase utilization of HIV services, improve linkages to services at the community level, and encourage the adoption of HIV risk reduction behaviors. Find out about the quantitative and qualitative results emerging from SOAR’s…

The Southern Africa HIV and AIDS Regional Exchange (SHARE) is pleased to present the latest issue of the research digest. The digest offers article abstracts from peer-reviewed literature related to HIV and AIDS in southern Africa and is designed to keep you in touch with the rapidly expanding…

INTRODUCTION: For HIV-positive individuals on antiretroviral therapy (ART), the World Health Organization (WHO) recommends routine viral load (VL) monitoring. We report on the cascade of care in individuals with unsuppressed VL after…

Increasing numbers of people living with HIV (PLHIV) in sub-Saharan Africa are experiencing failure of first-line antiretroviral therapy and transitioning onto second-line regimens. However, there is a dearth of research on their treatment experiences. We conducted in-…