Resource Library

The Partnership for HIV-Free Survival (PHFS) was designed to use basic quality improvement practices to reduce mother-to-child transmission of HIV and increase child survival through improvements in (1) antiretroviral therapy uptake and retention among HIV-positive pregnant women and mothers, (2…

This first progress report shows that members of the Global HIV Prevention Coalition have mobilized around strengthening HIV primary prevention. There are clear signs of renewed political commitment and strengthened institutional arrangements for planning and managing prevention programmes. Most…

Remarkable progress is being made on HIV treatment. Ahead of World AIDS Day, UNAIDS has launched a new report showing that access to treatment has risen significantly. In 2000, just 685 000 people living with HIV had access to antiretroviral therapy. By June 2017, around 20.9 million people had…

This report compiles the latest body of evidence on how stigma and discrimination create barriers across the HIV prevention, testing and treatment cascades and reduce the impact of the AIDS response. The report also brings together best practices on confronting stigma and discrimination,…

This report documents progress on implementation of a Swedish International Development Cooperation Agency (Sida)-funded UNESCO project that aims to strengthen sexuality education programmes for young people in school settings in Zambia. The project was conceptualized in line with the country’s…

Adolescents are unique in their development, their health and their social needs; therefore, their service requirements are different. The developmental changes experienced during adolescence make it one of the most rapidly changing stages of life. These changes impact on adolescents’ health,…

Angola has a generalized, heterosexually-driven HIV epidemic with an adult prevalence of 2.42 percent, according to 2014 estimates from the Joint United Nations Programme on HIV/AIDS (UNAIDS 2014a). The proportion of women receiving ART to prevent mother-to-child transmission (MTCT) of HIV has…

Angola has a generalized, heterosexually-driven HIV epidemic with an adult prevalence of 2.42 percent, according to 2014 estimates from the Joint United Nations Programme on HIV/AIDS (UNAIDS 2014a). The proportion of women receiving ART to prevent mother-to-child transmission (MTCT) of HIV has…

The past decade has seen tremendous progress in making services to prevent mother-to-child transmission of HIV (PMTCT) services more available in many HIV high-prevalence settings. Despite this progress, new HIV infections among pregnant women, newborns, and infants remain unacceptably high, and…

Objective: This prospective study investigated the relationship between male antenatal clinic (ANC) involvement and infant HIV-free survival.

Methods: From 2009 to 2013, HIV-infected pregnant women were enrolled from 6 ANCs in Nairobi,…

Timely access to antiretroviral treatment (ART) is vital to ensuring safe motherhood and reducing vertical transmission. Treatment guidance and programming has changed dramatically in recent years. While progress has been made in improving maternal health, more is needed, including efforts to…

Lactation studies are necessary evaluations of medications for reproductive-age women. We evaluated pharmacokinetics (PK), pharmacodynamics, safety, and adherence profiles associated with 7 days of 1% tenofovir (TFV) vaginal gel use during lactation. Tenofovir levels (maternal/infant serum, milk…

Addressing gender norms and inequities is essential to reducing HIV risk, mitigating its impact, and increasing access to services for men and women. The U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) promotes the integration of gender throughout its prevention, care, and treatment…

MANET+, the national coordinating body for community-based support groups in Malawi, was founded in 1997 by a group of PLHIV who recognized the need to organize their activities to achieve greater impact on national HIV policies. This case study analyzes the engagement of CSOs in PMTCT policy…

The number of infants infected with HIV is declining with the rise in interventions for the elimination of paediatric HIV infection, but the number of uninfected infants exposed to HIV through their HIV-infected mothers is increasing. Interest in the health outcomes of HIV-exposed, uninfected…

The U.S. Agency for International Development's (USAID's) 2014 Acting on the Call Report formulated country-specific plans for working with partners in 24 priority countries to save the lives of mothers and children. The follow-up 2015 Acting on the Call Report provided country-by-country…

Since the late 1990s, by providing services to prevent mother-to-child transmission of HIV, many countries have made significant progress toward eliminating new HIV infections in children. The introduction and rollout of Option B+ was a contributing factor in these achievements and an important…

As part of Disease Control Priorities 3rd Edition, the World Bank will publish a volume on Reproductive, Maternal, Newborn, and Child Health that identifies essential cost-effective health interventions that can be scaled up to reduce maternal, newborn, and child deaths, and…

Background:

HIV-infected women risk sexual and perinatal HIV transmission during conception, pregnancy, childbirth, and breastfeeding. We compared HIV-1 RNA suppression and medication adherence across periconception, pregnancy, and postpartum periods, among women on…

This supplement to Acta Paediatrica presents a series of meta-analyses and systematic literature reviews examining a variety of health effects potentially related to breastfeeding. The authors carefully study a wide breadth of the literature to describe current…

This is the fourth annual report of the Global Plan, and it summarizes the progress made through December 2014. The final accountability report of the Global Plan will be…

BACKGROUND:

South Africa (SA) is likely to meet the National Strategic Plan target of

OBJECTIVE: To evaluate the impact of substituting this recommendation for the post-weaning HIV testing recommended by SA guidelines. 

METHODS…

Introduction

Male involvement (MI) is vital for the uptake of Prevention of Mother to Child Transmission (PMTCT) of Human Immunodeficiency Virus (HIV) interventions. Partner notification (PN) is among the strategies identified for MI in PMTCT services. The purpose of this…

The National Department of Health (NDOH) commissioned a Joint Review of the HIV, TB and PMTCT Programmes to be undertaken in 2013. The main purpose of this independent Review, carried out by a multi-disciplinary team of South African and international reviewers, was to assess performance of the…

In Zambia’s Southern Province, the Community PMTCT Follow-up Register Project is improving access and adherence to HIV testing and treatment for pregnant women and their children. The program works through a specialized register and uses outreach and follow-up by trained lay counselors to…

In guidelines released in 2010, the World Health Organization recommends that health facilities integrate prevention of mother-to-child transmission (PMTCT) with maternal, newborn, and child health (MNCH) services to improve patient follow-up and adherence. This report describes the results of…

HIV presents an increasing risk to pregnant women, their infants, and their families. In response, governments are looking to the integration of two services traditionally provided separately: maternal, newborn, and child health (MNCH) and prevention of mother-to-child transmission (PMTCT) of…