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Increasing numbers of people living with HIV (PLHIV) in sub-Saharan Africa are experiencing failure of first-line antiretroviral therapy and transitioning onto second-line regimens. However, there is a dearth of research on their treatment experiences. We conducted in-…

Increasing numbers of people living with HIV (PLHIV) in sub-Saharan Africa are experiencing failure of first-line antiretroviral therapy and transitioning onto second-line regimens. However, there is a dearth of research on their treatment experiences. We conducted in-depth interviews with 43…

BACKGROUND: In Malawi's PMTCT Option B+ program, HIV-infected pregnant women who are already receiving ART are continued on…

USAID and PEPFAR's approach to pursuing HIV epidemic control is transforming lives and supporting the development of healthy, self-reliant Malawian people. This video demonstrates how partners are collaborating to bring HIV services to hard-to-reach populations, such as fishermen. …

In late 2015, the Linkages Across the Continuum of HIV Services for Key Populations (LINKAGES) project established a global acceleration initiative to fast-track and strengthen delivery of a comprehensive package of health services for key populations (KPs) at scale. In this context, “…

Sub-Saharan Africa bears more than two-thirds of the worldwide burden of HIV; however, data among transgender women from the region are sparse. Transgender women across the world face significant vulnerability to HIV. This analysis aimed to assess HIV prevalence as well as psychosocial and…

The life expectancy of HIV-positive individuals receiving antiretroviral therapy (ART) is approaching that of HIV-negative people. However, little is known about how these populations compare in terms of health-related quality of life (HRQoL). We aimed to compare HRQoL between HIV-positive and…

This multi-country trial examined outcomes among treatment-naïve adults and children with CD4 counts below 100 who were given enhanced antimicrobial prophylaxis including trimethoprim-sulfamethoxazole, isoniazid-pyridoxine, fluconazole, azithromycin, and albendazole in addition to antiretroviral…

This report presents progress made after two years of implementation of the ESA Commitment (2013-2015). Significant progress has already been made thanks to concerted action by governments, civil society, and development partners at national and regional level.

The data presented was…

DREAMS is an ambitious $385 million partnership to reduce HIV infections among adolescent girls and young women in 10 sub-Saharan African countries. The goal of DREAMS is to help girls develop into Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe women. Girls and young women…

East and Southern Africa carries the global burden of HIV/ AIDS and the impact of HIV/AIDS on children, adolescents and their families is tremendous. In collaboration with governments in four countries in the region, UNICEF conceived a ‘Cash Plus Care’ intervention in 2014, which aims to…