Pre-exposure prophylaxis (PrEP)

Resource
July 16, 2019
The Sub-Saharan Africa region still remains the epicentre of the global HIV/AIDS epidemic. With regards to new paediatric HIV infections, almost 90% of new HIV infections are among children (aged 0-14 years), largely through mother to child transmission. Male Partner Involvement in Prevention of Mother to Child Transmission programmes is now strongly advocated as being key in improving infant outcomes. This study describes the role of Male Partner Involvement on infant HIV infection and mortality survival in the first year among HIV-exposed infants born from HIV positive mothers.
Resource
June 28, 2019
This analysis offers a wide range of scenarios given the considerable uncertainty over ring uptake, consistency of use, and effectiveness, as well as HIV testing, prevention, and treatment use over the next two decades. This could help inform donors and implementers as they decide where to allocate resources in order to maximize the impact of the dapivirine ring in light of funding and implementation constraints.
Blog
June 27, 2019
The biennial South African AIDS Conference (SA AIDS 2019), which took place earlier this month in Durban, South Africa, was an opportunity to meet a diverse range of players in the field of HIV and AIDS -- and one of the most innovative and inspiring of these is definitely Grassroot Soccer (GRS), so the SHARE team was really excited to get the chance to chat with some of the organization’s coaches, or young adult mentors, and master trainers about the work they are doing and what brought them to the conference.
Resource
June 26, 2019
ARV-based pre-exposure prophylaxis (PrEP) has the potential to avert many new HIV infections, yet little is known about how to reach women at high risk for HIV infection and motivate them to initiate PrEP. Clinical trials have succeeded in recruiting at-risk participants, evidenced by control arm HIV incidence ≥3% (defined by the World Health Organization as “substantial risk”). We examined experiences from HIV prevention trials to document recruitment strategies and identify practical, potentially effective strategies for reaching women in real-world PrEP delivery.
Resource
April 12, 2019
One of the factors linked to South Africa's relatively high maternal mortality ratio is late utilization of antenatal care (ANC). Early utilization is especially important in South Africa due to the high HIV prevalence amongst pregnant women. This study examined the impact of a package intervention, consisting of an incentive called the Thula Baba Box (TBB) and a community health worker (CHW) programme, on early utilization of ANC.
Resource
April 12, 2019
Failing to account for constraints on allocative and technical efficiency can result in the overestimation of the health gains possible, and for technical inefficiencies the allocation of an inefficient strategy.
Resource
April 3, 2019

USAID’s Office of HIV/AIDS (OHA) and the Center for Innovation and Impact (CII) are excited to announce the launch of “V”, a human-centered design approach to addressing challenges in uptake and adherence for oral PrEP among adolescent girls and young women.

Resource
March 19, 2019

SheConquers, the South African national campaign that aims to improve the lives of adolescent girls and young women and their male peers in South Africa, held a 2-day workshop that accommodated 27 young people representing all 9 provinces from South Africa.

Blog
March 19, 2019

Incorporating stakeholder engagement early and deeply in the development of a clinical trial for HIV prevention research is for us a clarion call.

Resource
March 12, 2019

The ring introduction matrix is an early-stage implementation tool intended to help policymakers and implementers consider the introduction of the dapivirine ring alongside oral PrEP.